Structure information

NTS1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7L0Q

SPECIES

Rattus norvegicus

RESOLUTION

4.300

PREFERRED CHAIN

C

REFERENCE

PUBLICATION DATE

Jan. 6, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
neurotensin L55 N-term polar (hydrogen bond with backbone)
neurotensin F128 ECL1 hydrophobic
neurotensin H133 ECL1 polar (hydrogen bond)
neurotensin Y146 3.29x29 TM3 polar (charge-assisted hydrogen bond)
neurotensin V224 ECL2 hydrophobic
neurotensin R327 6.54x54 TM6 polar (charge-charge)
neurotensin F331 6.58x58 TM6 hydrophobic
neurotensin I334 6.61x61 TM6 polar (hydrogen bond with backbone)
neurotensin I334 6.61x61 TM6 polar (hydrogen bond with backbone)
neurotensin D336 ECL3 polar (charge-assisted hydrogen bond)
neurotensin D336 ECL3 polar (charge-charge)
neurotensin W339 ECL3 hydrophobic
neurotensin F344 7.28x27 TM7 hydrophobic
neurotensin Y347 7.31x30 TM7 polar (hydrogen bond)

Ligands

neurotensin

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Residue Diagrams

S N G V T G V V F L A L Y I A T V L V K 1 G S L A L S D L L I L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A I P M 4 N L I S I V L M P F L F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I A S S V Y F L A N T L M Y F Y 7
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ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G L Q N R S G D G T H P G G L V C T P I V D ECL2ICL3 R V C T V G T H N G L E H S T F N M T I E ICL3ECL3 S D E Q W ECL3N-term M H L N S S V P Q G T P G E P D A Q P F S G P Q S E M E A T F L A L S L S N G S G N T S E S D T A G P N S D L D V N T D N-termC-term P G W R H R R K K R P T F S R K P N S M S S N H A F S T S A T R E T L Y C-term I Y S K V L V T A I Y L A L F V V G T V G N S V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L I L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A I P M L F T M T A T V K V V I Q V N T F M S F L F P M L V I S I L N T V I A N K L T V M V H Q A A E Q G P G R V Q A L R H G V L V L R A V V I A F V V C W L P Y H V R R L M F C Y I T T F L F D F Y H Y F Y M L T N A L F Y V S S A I N P I L Y N L V S A N F L S L C F R Q V T L A C
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Residue Table


GPCRdb(A)
GPCRdb(A)
NTS1 receptor
TM3
3x29 3.29x29 Y146
TM6
6x54 6.54x54 R327
6x58 6.58x58 F331
6x61 6.61x61 I334
TM7
7x27 7.28x27 F344
7x30 7.31x30 Y347