Structure information

NTS1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7L0R

SPECIES

Rattus norvegicus

RESOLUTION

4.200

PREFERRED CHAIN

C

REFERENCE

PUBLICATION DATE

Jan. 6, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
neurotensin D54 N-term polar (charge-charge)
neurotensin L55 N-term hydrophobic
neurotensin H132 ECL1 polar (hydrogen bond with backbone)
neurotensin Y146 3.29x29 TM3 polar (charge-assisted hydrogen bond)
neurotensin M208 4.64x65 TM4 hydrophobic
neurotensin V224 ECL2 hydrophobic
neurotensin F331 6.58x58 TM6 polar (hydrogen bond with backbone)
neurotensin I334 6.61x61 TM6 polar (hydrogen bond with backbone)
neurotensin I334 6.61x61 TM6 polar (hydrogen bond with backbone)
neurotensin D336 ECL3 polar (charge-charge)
neurotensin D336 ECL3 polar (charge-assisted hydrogen bond)
neurotensin D336 ECL3 polar (charge-assisted hydrogen bond)
neurotensin W339 ECL3 polar (hydrogen bond)
neurotensin F344 7.28x27 TM7 hydrophobic
neurotensin Y347 7.31x30 TM7 polar (hydrogen bond)

Ligands

neurotensin

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Residue Diagrams

S N G V T G V V F L A L Y I A T V L V K 1 G S L A L S D L L I L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A I P M 4 N L I S I V L M P F L F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I A S S V Y F L A N T L M Y F Y 7
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ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G L Q N R S G D G T H P G G L V C T P I V D ECL2ICL3 R V C T V G T H N G L E H S T F N M T I E ICL3ECL3 S D E Q W ECL3N-term M H L N S S V P Q G T P G E P D A Q P F S G P Q S E M E A T F L A L S L S N G S G N T S E S D T A G P N S D L D V N T D N-termC-term P G W R H R R K K R P T F S R K P N S M S S N H A F S T S A T R E T L Y C-term I Y S K V L V T A I Y L A L F V V G T V G N S V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L I L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A I P M L F T M T A T V K V V I Q V N T F M S F L F P M L V I S I L N T V I A N K L T V M V H Q A A E Q G P G R V Q A L R H G V L V L R A V V I A F V V C W L P Y H V R R L M F C Y I T T F L F D F Y H Y F Y M L T N A L F Y V S S A I N P I L Y N L V S A N F L S L C F R Q V T L A C
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Residue Table


GPCRdb(A)
GPCRdb(A)
NTS1 receptor
TM3
3x29 3.29x29 Y146
TM4
4x65 4.64x65 M208
TM6
6x58 6.58x58 F331
6x61 6.61x61 I334
TM7
7x27 7.28x27 F344
7x30 7.31x30 Y347