Structure information

CCK1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7MBY

SPECIES

Homo sapiens

RESOLUTION

2.440

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

May 26, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Cholecystokinin-8 C94 2.57x56 TM2 polar (hydrogen bond)
Cholecystokinin-8 N98 2.61x60 TM2 polar (hydrogen bond)
Cholecystokinin-8 N98 2.61x60 TM2 polar (hydrogen bond)
Cholecystokinin-8 P101 2.64x63 TM2 polar (hydrogen bond with backbone)
Cholecystokinin-8 V125 3.36x36 TM3 hydrophobic
Cholecystokinin-8 Y176 4.60x61 TM4 hydrophobic
Cholecystokinin-8 F185 ECL2 hydrophobic
Cholecystokinin-8 R197 45.51x51 ECL2 polar (charge-charge)
Cholecystokinin-8 L217 5.46x461 TM5 hydrophobic
Cholecystokinin-8 R336 6.58x58 TM6 polar (charge-assisted hydrogen bond)
Cholecystokinin-8 R336 6.58x58 TM6 polar (charge-assisted hydrogen bond)
Cholecystokinin-8 S348 ECL3 polar (hydrogen bond)
Cholecystokinin-8 S348 ECL3 polar (hydrogen bond)
Cholecystokinin-8 I352 7.35x34 TM7 hydrophobic
Cholecystokinin-8 Y360 7.43x42 TM7 polar (hydrogen bond)
Cholecystokinin-8 Y360 7.43x42 TM7 polar (hydrogen bond)

Ligands

Cholecystokinin-8

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Residue Diagrams

T N G L V S L L F I L S Y L L I Q V A P 1 L S L A V S D L M L C F L C M P F N L I P 2 A V L N F T S V S V S T G M F Y T T T K 3 A L K V I A A T W C L S F T I M T P Y 4 Y A V M M V I G P I L F L I L L L F T H W 5 I V I V V L F F L C W M P I F S A N A W 6 I P N V C S S T Y S L L L I F S I P T 7
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ICL1 K R M R ICL1ECL1 D F I F ECL1ICL2 P L Q S R V W Q ICL2ECL2 N L V P F T K N N N Q T A N M C R F L L P ECL2ICL3 Q K K S A K E R K P S T T S S G K Y E D S D G C Y L Q K T R P P R K L E L R Q L S T G S S S R A N R I R S N S ICL3ECL3 T A S A E R R L S ECL3N-term M D V V D S L L V N G S N I T P P C E L G L E N E T L F C L D Q P R P S K E N-termC-term P G P P G A R G E V G E E E E G G T T G A S L S R F S Y S H M S A S V P P Q C-term W Q P A V Q I L L Y S L I F L L S V L G N T L V I T V L I R N T V T N I F L L S L A V S D L M L C L F C M P F N L I P N L L K G S A V C K T T T Y F M G T S V S V S T F N L V A I S L E R Y G A I C K T K S H A L K V I A A T W C L S F T I M T P Y P I Y S N D V M Q Q S W H T F L L L I L F L I P G I V M M V A Y G L I S L E L Y Q G I K F E A S S A A N L M A K K R V I R M L I V I V V L F F L C W M P I F S A N A W R A Y D G T P I S F I L L L S Y T S S C V N P I I Y C F M N K R F M A C P N F R L G T F P C
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Residue Table


GPCRdb(A)
GPCRdb(A)
CCK1 receptor
TM2
2x56 2.57x56 C94
2x60 2.61x60 N98
2x63 2.64x63 P101
TM3
3x36 3.36x36 V125
TM4
4x61 4.60x61 Y176
ECL2
45x51 45.51x51 R197
TM5
5x461 5.46x461 L217
TM6
6x58 6.58x58 R336
TM7
7x34 7.35x34 I352
7x42 7.43x42 Y360