Structure information

M2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7T96

SPECIES

Homo sapiens

RESOLUTION

3.220

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Jan. 25, 2023
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
acetylcholine Y104 3.33x33 TM3 hydrophobic
acetylcholine W400 6.48x48 TM6 hydrophobic
acetylcholine Y403 6.51x51 TM6 hydrophobic
acetylcholine Y426 7.39x38 TM7 hydrophobic
acetylcholine Y430 7.43x42 TM7 hydrophobic
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 5 of 5 entries

Ligands

acetylcholine

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Residue Diagrams

I N G I I T V L S L S G A V L V I F V V 1 F S L A C A D L I I G F V S M N L Y T L Y 2 I L L N M V S A N S V V Y D L A L W L D 3 A G M M I A A A W V L S F I L W A P A I 4 Y L V T M I I V P L Y F A A I A T G F T V 5 L A I L L A F I I T W A P Y N V M V L I 6 A P N I T S N I Y C L W Y G I T W V T 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term K T F E V V F I V L V A G S L S L V T I I G N I L V M V S I K V N T V N N Y F L F S L A C A D L I I G V F S M N L Y T L Y T V I G G P V V C D L W L A L D Y V V S N A S V M N L L I I S F D R Y F C V T K T T K M A G M M I A A A W V L S F I L W A P A I L F W Q F I V G N A A V T F G T A I A A F Y L P V I I M T V L Y W H I S R A S K S R I K K D K K E K P P P S R E K K V T R T I L A I L L A F I I T W A P Y N V M V L I N T F C P N T V W T I G Y W L C Y I N S T I N P A C Y A L C N A T F K H F K K T L L M
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Residue Table


GPCRdb(A)
GPCRdb(A)
M2 receptor
TM3
3x33 3.33x33 Y104
TM6
6x48 6.48x48 W400
6x51 6.51x51 Y403
TM7
7x38 7.39x38 Y426
7x42 7.43x42 Y430