Structure information

GPR139

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7VUJ

SPECIES

Homo sapiens

RESOLUTION

3.800

PREFERRED CHAIN

R

REFERENCE

10.1038/S41422-021-00591-W

PUBLICATION DATE

Dec. 29, 2021

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
JNJ-63533054 F109 3.33x33 TM3 hydrophobic
JNJ-63533054 I112 3.36x36 TM3 hydrophobic
JNJ-63533054 I169 ECL2 hydrophobic
JNJ-63533054 R244 6.51x51 TM6 polar (charge-assisted hydrogen bond)
JNJ-63533054 M247 6.54x54 TM6 Van der Waals
JNJ-63533054 I248 6.55x55 TM6 Van der Waals
JNJ-63533054 I248 6.55x55 TM6 hydrophobic
JNJ-63533054 H251 6.58x58 TM6 Van der Waals
JNJ-63533054 N271 7.39x38 TM7 polar (hydrogen bond)
JNJ-63533054 N271 7.39x38 TM7 Van der Waals
JNJ-63533054 L275 7.43x42 TM7 hydrophobic
JNJ-63533054 L275 7.43x42 TM7 Van der Waals

Ligands

JNJ-63533054

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

I N A P L G L C L L L S Y Y V V P V F 1 L A L A A A D I L V L F F I V F V D F L 2 P V T I W I S T H I S S F E L V E I I K 3 T R K V I V S V Y I T C F L T S I P Y 4 N L I F F I S C P V L Y V T F C H I W I L 5 F T I T S I F A T L W A P R I I M I L Y 6 F F N I A T N L L A L M N A I D S M I 7
Download: PNG | SVG
ICL1 Q L V A R R Q ICL1ECL1 N M Q ECL1ICL2 P L K Y H T V S ICL2ECL2 W P N I W T E D Y I S ECL2ICL3 S N F R L R ICL3ECL3 A P I Q ECL3N-term M E H T H A H L A A N S S L S W W S P G S A C G L G N-termC-term K C Q K Q P V Q F Y T N H N F S I T S S P W I S P A N S H C I K M L V Y Q Y D K N G K P I K V S P C-term F V P V V Y Y S L L L C L G L P A N I L T V I I L S K S S Y N Y L L A L A A A D I L V L F F I V F V D F L L E D F I L M P Q V P D K I I E V L E F S S I H T S I W I T V P L T I D R Y I A V C H Y P A R T R K V I V S V Y I T C F L T S I P Y Y W T S V H H V L I W I H C F T V Y L V P C S I F F I L N S I I V Y K L R R K G Y S T G K T T A I L F T I T S I F A T L W A P R I I M I L Y H L Y G N R W L V H I M S D I A N M L A L L N T A I N F F L Y C F I S K R A A A F F F R T M T L K A
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
GPR139
TM3
3x33 3.33x33 F109
3x36 3.36x36 I112
TM6
6x51 6.51x51 R244
6x54 6.54x54 M247
6x55 6.55x55 I248
6x58 6.58x58 H251
TM7
7x38 7.39x38 N271
7x42 7.43x42 L275