Structure information

MRGPRX2

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7VV6

SPECIES

Homo sapiens

RESOLUTION

3.300

PREFERRED CHAIN

R

REFERENCE

10.1038/S41586-021-04077-Y

PUBLICATION DATE

Dec. 1, 2021

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
compound 48/80 L22 N-term hydrophobic
compound 48/80 F170 ECL2 hydrophobic
compound 48/80 D184 5.40x40 TM5 polar (charge-assisted hydrogen bond)
compound 48/80 W243 6.55x55 TM6 Van der Waals
compound 48/80 W243 6.55x55 TM6 hydrophobic
compound 48/80 L247 6.59x59 TM6 hydrophobic
compound 48/80 L247 6.59x59 TM6 Van der Waals
compound 48/80 W248 6.60x60 TM6 Van der Waals
compound 48/80 W248 6.60x60 TM6 hydrophobic
compound 48/80 S253 ECL3 Van der Waals

Ligands

compound 48/80

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

G N G V L G V L A I F L I L F V P I L T 1 L S L A G A D F L F L C F Q I I N C L V 2 T S L M S L G A L Y A C T M V T T F F S 3 S A V V C V L L W A L S L L L S I L E G 4 S S G C L V M F L F I L W A A T I F D F 5 L L T V L V F L L C G L P F G I Q W F L 6 I P N A S S N L S S L V V S V P H I H 7
Download: PNG | SVG
ICL1 R R ICL1ECL1 I S I N F ECL1ICL2 P I W Y R C R R ICL2ECL2 G F L F S D G ECL2ICL3 S R G L ICL3ECL3 K D S D V ECL3N-term M D P T T P A W G T E S T T V N G N D Q A L L L L C G K E N-termC-term R K Q W R L Q Q P I L K L A L Q R A L Q D I A E V D H S E G C F R Q G T P E M S R S S L V C-term T L I P V F L I L F I A L V G L V G N G F V L W L L G F R M N A F S V Y V L S L A G A D F L F L C F Q I I N C L V Y L S N F F C S P S F F T T V M T C A Y L A G L S M L S T V S T E R C L S V L W P R H L S A V V C V L L W A L S L L L S I L E G K F C D S G W C Q T F D F I T A A W L I F L F M V L C G S S L A L L V R I L C G P L T R L Y L T I L L T V L V F L L C G L P F G I Q W F L I L W I W L F C H I H P V S V V L S S L N S S A N P I I Y F F V G S F
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
MRGPRX2
TM5
5x40 5.40x40 D184
TM6
6x55 6.55x55 W243
6x59 6.59x59 L247
6x60 6.60x60 W248