Structure information

mGlu3 receptor

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

7WIH

SPECIES

Homo sapiens

RESOLUTION

3.680

PREFERRED CHAIN

A

REFERENCE

10.1038/S41422-022-00623-Z

PUBLICATION DATE

March 16, 2022

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL4081453 R68 N-term polar (charge-assisted hydrogen bond)
CHEMBL4081453 S100 N-term Van der Waals
CHEMBL4081453 S149 N-term polar (hydrogen bond with backbone)
CHEMBL4081453 S149 N-term polar (hydrogen bond)
CHEMBL4081453 Y150 N-term hydrophobic
CHEMBL4081453 Y150 N-term Van der Waals
CHEMBL4081453 S151 N-term Van der Waals
CHEMBL4081453 A172 N-term Van der Waals
CHEMBL4081453 A172 N-term polar (hydrogen bond with backbone)
CHEMBL4081453 S173 N-term Van der Waals
CHEMBL4081453 T174 N-term Van der Waals
CHEMBL4081453 Y222 N-term hydrophobic
CHEMBL4081453 Y222 N-term Van der Waals
CHEMBL4081453 R277 N-term polar (charge-assisted hydrogen bond)
CHEMBL4081453 S278 N-term polar (hydrogen bond with backbone)
CHEMBL4081453 S278 N-term Van der Waals
CHEMBL4081453 D279 N-term Van der Waals
CHEMBL4081453 D301 N-term polar (charge-assisted hydrogen bond)
CHEMBL4081453 K389 N-term polar (charge-assisted hydrogen bond)

Ligands

CHEMBL4081453

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

C T C M F G L C A I T V P G I A W 1 Y I L L F G V G L S Y C M T F F F I 2 T L L A S Y C I A F S S G L G L R R L A 3 Q V F I C L G L I L V Q I V M V S V W L 4 A Y V T C L I V L I V D Y T L S I L M S 5 G F T M Y T T C I I W L A F L P I F Y V 6 G L V V F G S L S V S I C M T T T Q V R 7
Download: PNG | SVG
ICL1 T N N P L V K A S ICL1ECL1 A K P ECL1ICL2 D G V K N G A Q R P K F I ICL2ECL2 A P G T R R Y T L A E K R E T V I L K C N V ECL2ICL3 R K C P E N F N ICL3ECL3 S S D Y ECL3N-term M K M L T R L Q V L T L A L F S K G F L L S L G D H N F L R R E I K I E G D L V L G G L F P I N E K G T G T E E C G R I N E D R G I Q R L E A M L F A I D E I N K D D Y L L P G V K L G V H I L D T C S R D T Y A L E Q S L E F V R A S L T K V D E A E Y M C P D G S Y A I Q E N I P L L I A G V I G G S Y S S V S I Q V A N L L R L F Q I P Q I S Y A S T S A K L S D K S R Y D Y F A R T V P P D F Y Q A K A M A E I L R F F N W T Y V S T V A S E G D Y G E T G I E A F E Q E A R L R N I C I A T A E K V G R S N I R K S Y D S V I R E L L Q K P N A R V V V L F M R S D D S R E L I A A A S R A N A S F T W V A S D G W G A Q E S I I K G S E H V A Y G A I T L E L A S Q P V R Q F D R Y F Q S L N P Y N N H R N P W F R D F W E Q K F Q C S L Q N K R N H R R V C D K H L A I D S S N Y E Q E S K I M F V V N A V Y A M A H A L H K M Q R T L C P N T T K L C D A M K I L D G K K L Y K D Y L L K I N F T A P F N P N K D A D S I V K F D T F G D G M G R Y N V F N F Q N V G G K Y S Y L K V G H W A E T L S L D V N S I H W S R N S V P T S Q C S D P C A P N E M K N M Q P G D V C C W I C I P C E P Y E Y L A D E F T C M D C G S G Q W P T A D L T G C Y D L P E D Y I R W E D A N-termC-term N R F S V S G T G T T Y S Q S S A S T Y V P T V C N G R E V L D S T T S S L C-term W A I G P V T I A C L G F M C T C M V V T V F I K H G R E L C Y I L L F G V G L S Y C M T F F F I S P V I C A L R R L G L G S S F A I C Y S A L L T K T N C I A R I F S P S S Q V F I C L G L I L V Q I V M V S V W L I L E K D S S M L I S L T Y D V I L V I L C T V Y A F K T E A K F I G F T M Y T T C I I W L A F L P I F Y V T R V Q T T T M C I S V S L S G F V V L G C L F A P K V H I I L F Q P Q K H R L N V V T H L
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(C)
mGlu3 receptor