Structure information

FPR1

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7WVU

SPECIES

Homo sapiens

RESOLUTION

3.300

PREFERRED CHAIN

R

REFERENCE

10.1038/S41467-022-29361-X

PUBLICATION DATE

April 13, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
FME-LEU-PHE F102 3.29x29 TM3 hydrophobic
FME-LEU-PHE D106 3.33x33 TM3 polar (charge-assisted hydrogen bond)
FME-LEU-PHE L109 3.36x36 TM3 Van der Waals
FME-LEU-PHE L109 3.36x36 TM3 hydrophobic
FME-LEU-PHE F110 3.37x37 TM3 Van der Waals
FME-LEU-PHE F110 3.37x37 TM3 hydrophobic
FME-LEU-PHE R201 5.38x39 TM5 polar (charge-assisted hydrogen bond)
FME-LEU-PHE R205 5.42x43 TM5 polar (charge-assisted hydrogen bond)
FME-LEU-PHE W254 6.48x48 TM6 Van der Waals
FME-LEU-PHE W254 6.48x48 TM6 hydrophobic
FME-LEU-PHE Y257 6.51x51 TM6 polar (hydrogen bond)
FME-LEU-PHE Y257 6.51x51 TM6 polar (hydrogen bond)
FME-LEU-PHE I268 ECL3 hydrophobic
FME-LEU-PHE I268 ECL3 Van der Waals
FME-LEU-PHE V283 7.35x34 TM7 Van der Waals

Ligands

FME-LEU-PHE

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Residue Diagrams

G N G L V G L V F T V A F V L Y T I I D 1 L N L A V A D F C F T S T L P F F M V R 2 L A I L F V S G F L N I D V I T F V F K 3 A K K V I I G P W V M A L L L T L P V 4 Y S V A V I S M P A S F G I I F R I I G R 5 S F V A A A F F L C W S P Y Q V V A L I 6 M P N L C S N F F A L A S T V D V A I 7
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ICL1 T H ICL1ECL1 G H W P F ECL1ICL2 P V W T Q N H R ICL2ECL2 T T V P G K T G T V A C T F N F S P W T N ECL2ICL3 L I K S ICL3ECL3 I R E L L Q G M ECL3N-term M E T N S S L P T N I S G G T P A V N-termC-term P A S L E R A L T E D S T Q T S D T A T N S T L P S A E V E L Q A K C-term S A G Y L F L D I I T Y L V F A V T F V L G V L G N G L V I W V A G F R M T V T T I S Y L N L A V A D F C F T S T L P F F M V R K A M G G W F L C K F V F T I V D I N L F G S V F L I A L I A L D R C V C V L H T V S L A K K V I I G P W V M A L L L T L P V I I R V D P K E R I N V A V A M L T V R G I I R F I I G F S A P M S I V A V S Y G L I A T K I H K Q G S R P L R V L S F V A A A F F L C W S P Y Q V V A L I A T V R Y K E I G I A V D V T S A L A F F N S C L N P M L Y V F M G Q D L I H F R E R A L
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Residue Table


GPCRdb(A)
GPCRdb(A)
FPR1
TM3
3x29 3.29x29 F102
3x33 3.33x33 D106
3x36 3.36x36 L109
3x37 3.37x37 F110
TM5
5x39 5.38x39 R201
5x43 5.42x43 R205
TM6
6x48 6.48x48 W254
6x51 6.51x51 Y257
TM7
7x34 7.35x34 V283