Structure information

FPR2/ALX

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7WVX

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

R

PUBLICATION DATE

April 13, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
humanin E89 ECL1 polar (charge-assisted hydrogen bond)
humanin D106 3.33x33 TM3 polar (charge-assisted hydrogen bond)
humanin L109 3.36x36 TM3 hydrophobic
humanin F110 3.37x37 TM3 hydrophobic
humanin I169 ECL2 hydrophobic
humanin Y175 ECL2 aromatic (face-to-edge)
humanin N179 ECL2 polar (hydrogen bond)
humanin N179 ECL2 polar (hydrogen bond)
humanin F180 ECL2 polar (hydrogen bond with backbone)
humanin A181 ECL2 hydrophobic
humanin L198 5.35x36 TM5 hydrophobic
humanin R201 5.38x39 TM5 polar (charge-assisted hydrogen bond)
humanin R201 5.38x39 TM5 polar (charge-assisted hydrogen bond)
humanin R205 5.42x43 TM5 polar (charge-assisted hydrogen bond)
humanin F257 6.51x51 TM6 hydrophobic
humanin Q258 6.52x52 TM6 polar (hydrogen bond)

Ligands

humanin

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Residue Diagrams

G N G L V G L V F T V G L V V L P L I R 1 L N L A L A D F S F T A T L P F L I V S 2 F G I L F V S G F L N I D V V I H I L K 3 A M K V I V G P W I L A L V L T L P V 4 Y C I A V I S M P L S F G I V F R I I G R 5 T A V V A S F F I C W F P F Q L V A L L 6 M P N L C S N F F A L S S T P N V L I 7
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ICL1 T R ICL1ECL1 E K W P F ECL1ICL2 P V W A Q N H R ICL2ECL2 T T V T I P N G D T Y C T F N F A S W G G ECL2ICL3 M I K S ICL3ECL3 L K E M L F Y G K ECL3N-term M E T N F S T P L N E Y E E V S Y E N-termC-term P T S L E R A L S E D S A P T N D T A A N S A S P P A E T E L Q A M C-term S A G Y T V L R I L P L V V L G V T F V L G V L G N G L V I W V A G F R M T V T T I C Y L N L A L A D F S F T A T L P F L I V S M A M G G W F L C K L I H I V V D I N L F G S V F L I G F I A L D R C I C V L H T V S L A M K V I V G P W I L A L V L T L P V F L F L T P E E R L K V A I T M L T A R G I I R F V I G F S L P M S I V A I C Y G L I A A K I H K K G S R P L R V L T A V V A S F F I C W F P F Q L V A L L G T V W Y K I I D I L V N P T S S L A F F N S C L N P M L Y V F V G Q D L I H F R E R S L
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Residue Table


GPCRdb(A)
GPCRdb(A)
FPR2/ALX
TM3
3x33 3.33x33 D106
3x36 3.36x36 L109
3x37 3.37x37 F110
TM5
5x36 5.35x36 L198
5x39 5.38x39 R201
5x43 5.42x43 R205
TM6
6x51 6.51x51 F257
6x52 6.52x52 Q258