Structure information

SST4 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7XMT

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

R

REFERENCE

10.1038/S41422-022-00679-X

PUBLICATION DATE

Aug. 3, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
J-2156 V103 2.60x60 TM2 hydrophobic
J-2156 W112 23.50x50 ECL1 hydrophobic
J-2156 L123 3.29x29 TM3 hydrophobic
J-2156 D126 3.32x32 TM3 polar (charge-assisted hydrogen bond)
J-2156 M130 3.36x36 TM3 Van der Waals
J-2156 M130 3.36x36 TM3 hydrophobic
J-2156 F131 3.37x37 TM3 hydrophobic
J-2156 F131 3.37x37 TM3 Van der Waals
J-2156 N199 45.51x51 ECL2 Van der Waals
J-2156 L200 45.52x52 ECL2 Van der Waals
J-2156 V212 5.39x40 TM5 hydrophobic
J-2156 T215 5.42x43 TM5 Van der Waals
J-2156 F275 6.51x51 TM6 hydrophobic
J-2156 F275 6.51x51 TM6 Van der Waals
J-2156 Y276 6.52x52 TM6 Van der Waals
J-2156 Y276 6.52x52 TM6 hydrophobic
J-2156 Q279 6.55x55 TM6 Van der Waals
J-2156 Q279 6.55x55 TM6 polar (hydrogen bond)

Ligands

J-2156

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Residue Diagrams

A N G V L G V L C V L A Y I C Q I A V M 1 L N L A V A D E L F M L S V P F V A S S 2 V T L C F V S T F M N L G D V S L V A R 3 A K L I N L G V W L A S L L V T L P I 4 Y C L G I A L V P L L F G L L F T Y V V F 5 L M V V V V F V L C W M P F Y V V Q L L 6 I P N A C S N A Y S L I L S V H N V T 7
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ICL1 A K M K ICL1ECL1 R H W P F ECL1ICL2 P L R A A T Y R ICL2ECL2 D T R P A R G G Q A V A C N L Q W P ECL2ICL3 A L R A G ICL3ECL3 T S L D ECL3N-term M S A P S T L P P G G E E G L G T A W P S A A N A S S A P A E A E E A V A G P G D A R N-termC-term L R C C L L E G A G G A E E E P L D Y Y A T A L K S K G G A G C M C P P L P C Q Q E A L Q P E P G R K R I P L T R T T T F C-term A A G M V A I Q C I Y A L V C L V G L V G N A L V I F V I L R Y T A T N I Y L L N L A V A D E L F M L S V P F V A S S A A L G S V L C R A V L S V D G L N M F T S V F C L T V L S V D R Y V A V V H R P S V A K L I N L G V W L A S L L V T L P I A I F A H P A W S A V F V V Y T F L L G F L L P V L A I G L C Y L L I V G K M R A V W Q Q R R R S E K K I T R L V L M V V V V F V L C W M P F Y V V Q L L N L F V A T V N H V S L I L S Y A N S C A N P I L Y G F L S D N F Q R F R R F V L C
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Residue Table


GPCRdb(A)
GPCRdb(A)
SST4 receptor
TM2
2x60 2.60x60 V103
ECL1
23x50 23.50x50 W112
TM3
3x29 3.29x29 L123
3x32 3.32x32 D126
3x36 3.36x36 M130
3x37 3.37x37 F131
ECL2
45x51 45.51x51 N199
45x52 45.52x52 L200
TM5
5x40 5.39x40 V212
5x43 5.42x43 T215
TM6
6x51 6.51x51 F275
6x52 6.52x52 Y276
6x55 6.55x55 Q279