Structure information

κ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8DZQ

SPECIES

Homo sapiens

RESOLUTION

2.820

PREFERRED CHAIN

A

REFERENCE

10.1038/S41586-023-06030-7

PUBLICATION DATE

May 3, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
SALVINORIN B METHOXYMETHYL ETHER L135 3.29x29 TM3 hydrophobic
SALVINORIN B METHOXYMETHYL ETHER M142 3.36x36 TM3 hydrophobic
SALVINORIN B METHOXYMETHYL ETHER W287 6.48x48 TM6 hydrophobic
SALVINORIN B METHOXYMETHYL ETHER I294 6.55x55 TM6 hydrophobic
SALVINORIN B METHOXYMETHYL ETHER Y312 7.35x34 TM7 hydrophobic
SALVINORIN B METHOXYMETHYL ETHER I316 7.39x38 TM7 hydrophobic
SALVINORIN B METHOXYMETHYL ETHER Y320 7.43x42 TM7 hydrophobic

Ligands

SALVINORIN B METHOXYMETHYL ETHER

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Residue Diagrams

S N G V L G V V F V V S Y V A T I I V P 1 F N L A L A D A L V T T T M P F Q S T V 2 M T L T F I S T F M N Y Y D I S I V I K 3 A K I I N I C I W L L S S S V G I S A I 4 Y C V I I I L V P I V F A F I F V C I K M 5 L V V V A V F V V C W T P I H I F I L V 6 I P N L S S N T Y G L A I C F Y Y S S 7
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ICL1 T K M K ICL1ECL1 S W P F ECL1ICL2 P V K A L D F R ICL2ECL2 G T K V R E D V D V I E C S L Q F P D D ECL2ICL3 R L L S G ICL3ECL3 S T S H ECL3N-term M D S P I Q I F R G E P G P T C A P S A C L P P N S S A W F P G W A E P D S N G S A G S E D A Q L E P A H I S P N-termC-term P L K M R M E R Q S T S R V R N T V Q D P A Y L R D I D G M N K P V C-term A I P V I I T A V Y S V V F V V G L V G N S L V M F V I I R Y T A T N I Y I F N L A L A D A L V T T T M P F Q S T V Y L M N G D V L C K I V I S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P L K A K I I N I C I W L L S S S V G I S A I V L G D Y S W W D L F M K I C V F I F A F V I P V L I I I V C Y T L M I L R L K S V S R E K D R N L R R I T R L V L V V V A V F V V C W T P I H I F I L V E A L G S T A A L S S Y Y F C I A L G Y T N S S L N P I L Y A F L D E N F R D F K R C F C F
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Residue Table


GPCRdb(A)
GPCRdb(A)
κ receptor
TM3
3x29 3.29x29 I135
3x36 3.36x36 M142
TM6
6x48 6.48x48 W287
6x55 6.55x55 I294
TM7
7x34 7.35x34 Y312
7x38 7.39x38 I316
7x42 7.43x42 Y320