Structure information

OR51E2

PROTEIN CLASS

Class O1 (fish-like odorant)

PDB CODE

8F76

SPECIES

Homo sapiens

RESOLUTION

3.100

PREFERRED CHAIN

A

REFERENCE

10.1038/S41586-023-05798-Y

PUBLICATION DATE

March 22, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
propanoic acid H180 45.52x52 ECL2 polar (hydrogen bond)
propanoic acid H180 45.52x52 ECL2 Van der Waals
propanoic acid G198 5.39x40 TM5 polar (hydrogen bond with backbone)
propanoic acid G198 5.39x40 TM5 Van der Waals

Ligands

propanoic acid

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Residue Diagrams

C N G F M A V V Y M S L L P F G V W F H 1 C M L A A I D L A L S T S T M P K I L A 2 A L L I T S E I A S L A H I F F M Q T L 3 T A Q I G I V A V V R G S L F F F P L P 4 Y S L S I F M V D V G M V L L I A T L G Y 5 V S H I G V V L A F Y V P L I G L S V V 6 I P N I V P P L L L Y I D G M V V R V 7
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ICL1 R S L H ICL1ECL1 S R E I ECL1ICL2 P L R H A A V L ICL2ECL2 A F C H S N V L S H S Y C V H Q D V M K L A Y A D ECL2ICL3 P ICL3ECL3 N S L ECL3N-term M S S C N F T H A T F V L I G I P G L E K N-termC-term S C D K D L Q A V G G K C-term A H F W V G F P L L S M Y V V A M F G N C I V V F I V R T E A P M Y L F L C M L A A I D L A L S T S T M P K I L A L F W F D S F E A C L T Q M F F I H A L S A I E S T I L L A M A F D R Y V A I C H N N T V T A Q I G I V A V V R G S L F F F P L P L L I K R L T L P N V V Y G L T A I L L V M G V D V M F I S L S Y F L I I R T V L Q L S K S E R A K A F G T C V S H I G V V L A F Y V P L I G L S V V H R F G H P I V R V V M G D I Y L L L P P V I N P I I Y G A K T K Q V L A I R T R M F K I
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Residue Table


GPCRdb(A)
GPCRdb(A)
OR51E2
ECL2
45x52 45.52x52 H180
TM5
5x40 5.39x40 G198