Structure information

CXCR3

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8HNN

SPECIES

Homo sapiens

RESOLUTION

3.600

PREFERRED CHAIN

R

REFERENCE

10.1038/S41594-023-01175-5

PUBLICATION DATE

Nov. 29, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL1921858 F224 5.47x47 TM5 hydrophobic
CHEMBL1921858 L228 5.51x51 TM5 hydrophobic
CHEMBL1921858 M231 5.54x54 TM5 hydrophobic
CHEMBL1921858 Y235 5.58x58 TM5 hydrophobic
CHEMBL1921858 L239 5.62x62 TM5 hydrophobic
CHEMBL1921858 V266 6.38x38 TM6 hydrophobic
CHEMBL1921858 A273 6.45x45 TM6 hydrophobic

Ligands

CHEMBL1921858

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Residue Diagrams

G N G L L G L L F L L S Y L A P L F A R 1 L H L A V A D T L L V L T L P L W A V D 2 C A L L L A G A Y F N I N F L A G A V K 3 V T L T C L A V W G L C L L F A L P D 4 Y C Y A M V L L P L L F G A V L Q L V R L 5 V V V V V A F A L C W T P Y H L V V L V 6 L P N L C C H M Y G L G S T V S K A V 7
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ICL1 R T A L ICL1ECL1 Q W V F ECL1ICL2 A T Q L Y R R G P P ICL2ECL2 S A H H D E R L N A T H C Q Y N F ECL2ICL3 R G Q ICL3ECL3 A L A R ECL3N-term M V L E V S D H Q V L N D A E V A A L L E N F S S S Y D Y G E N E S D S C C T S P P C P N-termC-term G C P N Q R G L Q R Q P S S S R R D S S W S E T S E A S Y S G L C-term Q D F S L N F D R A F L P A L Y S L L F L L G L L G N G A V A A V L L S R S S T D T F L L H L A V A D T L L V L T L P L W A V D A A V G S G L C K V A G A L F N I N F Y A G A L L L A C I S F D R Y L N I V H A R V T L T C L A V W G L C L L F A L P D F I F L P Q V G R T A L R V L Q L V A G F L L P L L V M A Y C Y A H I L A V L L V S R R L R A M R L V V V V V V A F A L C W T P Y H L V V L V D I L M D L G N C G R E S R V D V A K S V T S G L G Y M H C C L N P L L Y A F V G V K M W M L F R E R L L L R
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Residue Table


GPCRdb(A)
GPCRdb(A)
CXCR3
TM5
5x47 5.47x47 F224
5x51 5.51x51 L228
5x54 5.54x54 M231
5x58 5.58x58 Y235
5x62 5.62x62 L239
TM6
6x38 6.38x38 V258
6x45 6.45x45 A265