Structure information

Olfactory receptor 52E4

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8HTI

SPECIES

Homo sapiens

RESOLUTION

2.970

PREFERRED CHAIN

R

REFERENCE

10.1038/S41467-023-43983-9

PUBLICATION DATE

Dec. 20, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
OCTANOIC ACID F161 4.60x60 TM4 hydrophobic
OCTANOIC ACID H183 45.52x52 ECL2 polar (hydrogen bond)
OCTANOIC ACID H183 45.52x52 ECL2 Van der Waals
OCTANOIC ACID I208 5.47x47 TM5 hydrophobic
OCTANOIC ACID I208 5.47x47 TM5 Van der Waals
OCTANOIC ACID F261 6.55x55 TM6 Van der Waals
OCTANOIC ACID F261 6.55x55 TM6 hydrophobic

Ligands

OCTANOIC ACID

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Residue Diagrams

M N G V I A I L Y V I C F P F S I W I H 1 A M L S M I D L G L S S T T I P K M L G I 2 V V L L V T E M G T F M H I F F M Q L L 3 I S I L A S V V V G R N L V L V T P F V 4 Y S S A I L I V D V I I Y S I V M L G Y 5 G S H V C V M L C F Y T P A F F S F M T 6 V P N L A P P V V V Y L N A L L I H I 7
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ICL1 H S L H ICL1ECL1 L Q E I ECL1ICL2 P L Q Y T M I L ICL2ECL2 P F C G H N I V P H T Y C E H R G L A G L A C A P ECL2ICL3 P ICL3ECL3 Q N I ECL3N-term M P S I N D T H F Y P P F F L L L G I P G L D T L N-termC-term K E C-term H I W I S F P F C I V Y L I A I V G N M T I L F V I K T E Q P M F Y F L A M L S M I D L G L S T S T I P K M L G I F W F N S F G G C L L Q M F F I H M F T G M E T V L L V V M A Y D R F V A I C N T N K T I S I L A S V V V G R N L V L V T P F V F L I L R L I K I N I I Y G L M V I S Y I I V D V I L I A S S Y V L I L R A V F R L S Q D V R L K A F N T C G S H V C V M L C F Y T P A F F S F M T H R F G P H Y I H I L L A N L Y V V V P P A L N P V I Y G V R T K Q I V K I R E Q I F V Q
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Residue Table


GPCRdb(A)
GPCRdb(A)
Olfactory receptor 52E4
TM4
4x60 4.60x60 F161
ECL2
45x52 45.52x52 H183
TM5
5x47 5.47x47 I208
TM6
6x55 6.55x55 F260