PDB
8IEI
Resolution
2.6 Å
Released
Feb. 14, 2024
Receptor
GPR156
Class
C
Species
Homo sapiens
Ligand
Function
PC 34:1
Agonist
Reference
—

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
PC 34:1 T98 2.49x49 TM2 hydrophobic
PC 34:1 F105 2.56x56 TM2 Van der Waals
PC 34:1 L124 3.33x33 TM3 Van der Waals
PC 34:1 L127 3.36x36 TM3 hydrophobic
PC 34:1 C128 3.37x37 TM3 Van der Waals
PC 34:1 T131 3.40x40 TM3 hydrophobic
PC 34:1 F135 3.44x44 TM3 Van der Waals
PC 34:1 W183 4.50x50 TM4 hydrophobic
PC 34:1 I189 ECL2 Van der Waals
PC 34:1 F215 ECL2 aromatic (pi-cation)
PC 34:1 C216 45.50x50 ECL2 Van der Waals
PC 34:1 A217 45.51x51 ECL2 Van der Waals
PC 34:1 S218 45.52x52 ECL2 Van der Waals
PC 34:1 S221 5.36x36 TM5 Van der Waals
PC 34:1 I225 5.40x40 TM5 hydrophobic
PC 34:1 I228 5.43x43 TM5 hydrophobic
PC 34:1 W229 5.44x44 TM5 hydrophobic
PC 34:1 K232 5.47x47 TM5 hydrophobic
PC 34:1 G233 5.48x48 TM5 Van der Waals
PC 34:1 L236 5.51x51 TM5 hydrophobic
PC 34:1 L267 6.45x45 TM6 hydrophobic
PC 34:1 V268 6.46x46 TM6 Van der Waals
PC 34:1 A271 6.49x49 TM6 hydrophobic
PC 34:1 L274 6.52x52 TM6 hydrophobic
PC 34:1 F275 6.53x53 TM6 Van der Waals
PC 34:1 T278 6.56x56 TM6 Van der Waals
PC 34:1 R279 6.57x57 TM6 polar (hydrogen bond)
PC 34:1 R279 6.57x57 TM6 polar (charge-charge)
PC 34:1 T292 7.32x33 TM7 Van der Waals
PC 34:1 I296 7.36x37 TM7 hydrophobic
PC 34:1 C299 7.39x40 TM7 Van der Waals
PC 34:1 T300 7.40x41 TM7 Van der Waals
PC 34:1 I303 7.43x44 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 N R K R I V K M S ICL1ECL1 Q D V L ECL1ICL2 Q R V P D K R V I I ICL2ECL2 P I Q C L Q I L S V S M T V T G K D V S C T S T S T H F C A S R ECL2ICL3 S S P P V N Q ICL3ECL3 S ECL3N-term M E P E I N C S E L C D S F P G Q E L D R R P L H D L C K T T I T S S H H S S K T I S S L N-termC-term Y F S T P N K S F H T Q Y G E E E N C H P R G E K S S M E R L L T E K N A V I E S L Q E Q V N N A K E K I V R L M S A E C T Y D L P E G A A P P A S S P N K D V Q A V A S V H T L A A A Q G P S G H L S D F Q N D P G M A A R D S Q C T S G P S S Y A Q S L E G P G K D S S F S P G K E E K I S D S K D F S D H L D S G C S Q K P W T E Q S L G P E R G D Q V P M N P S Q S L L P E R G G S D P Q R Q R H L E N S E E P P E R R S R V S S V I R E K L Q E V L Q D L G L G P E A S L S T A P S C H Q Q T W K N S A A F S P Q K M P L S K E L G F S P Y M V R R R R A A Q R A R S H F P G S A P S S V G H R A N R T V P G A H S R L H V Q N G D S P S L A P Q T T D S R V R R P S S R K P S L P S D P Q D R P G T L E G S K Q S Q T E P E G A R G S K A A F L R Q P S G S G R A P S P A A P C L S K A S P D L P E Q W Q L W P P V P S G C A S L S S Q H S Y F D T E S S S S D E F F C R C H R P Y C E I C F Q S S S D S S D S G T S D T D P E P T G G L A S W E K L W A R S K P I V N F K D D L K P T L V C-term S P V L L G I V W T F L S C G L L L I L F F L A F T I H C S P N L N I V T L L G S C L T Y S S A Y L F G I V G S S M E T L I Q T R L S M L C I G T S L V F G P I L G K S W R L Y K V F T K D L Q L L G L V A A L L M A D V I L L M T W V L T D Y S D V W I A L I W G C K G L L L L Y G A Y L A G L T G H V S L T I M V G V N L L V L A A G L L F V V T R Y L H W P N L V F G L T S G G I F V C T T T I N C F I F I P Q L K Q W K A F E E E R R M N Q T I A K
Helix box plot — Download: PNG | SVG L I L L L G C S L F T W V I G L L V P S 1 I V T L L G S C L T Y S S A Y L F G I 2 G L I P G F V L S T G I C L M S L R T Q 3 L L G L V A A L L M A D V I L L M T W V 4 A L Y A G Y L L L L G K C G W I L A I W 5 V G V N L L V L A A G L L F V V T R Y L 6 C N I T T T C V F I G G S T L G F V L N 7

GPCRdb(A)
GPCRdb(C)
GPR156
TM2
2x53 2.49x49 T98
2x60 2.56x56 F105
TM3
3x29 3.33x33 L124
3x32 3.36x36 L127
3x33 3.37x37 C128
3x36 3.40x40 T131
3x40 3.44x44 F135
TM4
4x60 4.50x50 W183
ECL2
45x50 45.50x50 C216
45x51 45.51x51 A217
45x52 45.52x52 S218
TM5
5x36 5.36x36 S221
5x40 5.40x40 I225
5x43 5.43x43 I228
5x44 5.44x44 W229
5x47 5.47x47 K232
5x48 5.48x48 G233
5x51 5.51x51 L236
TM6
6x43 6.45x45 L267
6x44 6.46x46 V268
6x47 6.49x49 A271
6x50 6.52x52 L274
6x51 6.53x53 F275
6x54 6.56x56 T278
6x55 6.57x57 R279
TM7
7x38 7.32x33 T292
7x42 7.36x37 I296
7x45 7.39x40 C299
7x46 7.40x41 T300
7x49 7.43x44 I303