Structure information

TAAR9

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8IW4

SPECIES

Mus musculus

RESOLUTION

3.490

PREFERRED CHAIN

R

REFERENCE

10.1038/S41586-023-06106-4

PUBLICATION DATE

May 31, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
SPERMIDINE T109 3.29x29 TM3 polar (hydrogen bond)
SPERMIDINE T109 3.29x29 TM3 Van der Waals
SPERMIDINE D112 3.32x32 TM3 polar (charge-assisted hydrogen bond)
SPERMIDINE T113 3.33x33 TM3 Van der Waals
SPERMIDINE T113 3.33x33 TM3 polar (hydrogen bond)
SPERMIDINE Y274 6.51x51 TM6 hydrophobic
SPERMIDINE Y274 6.51x51 TM6 Van der Waals
SPERMIDINE V297 7.39x38 TM7 hydrophobic
SPERMIDINE V297 7.39x38 TM7 Van der Waals
SPERMIDINE V300 7.42x41 TM7 Van der Waals
SPERMIDINE V300 7.42x41 TM7 hydrophobic
SPERMIDINE Y301 7.43x42 TM7 Van der Waals

Ligands

SPERMIDINE

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Residue Diagrams

L N G F V A L L A G L G L V G Y L I A R 1 A S L A C A D F L V G T V V M P F S T V R 2 C C L H F L S A F C F S T D F C T H F K 3 S G L C I A L S W F F S V T Y S F S I F 4 Y L F V M V V T P L F F L L F C L L V W 5 G I A M A A F L V S W L P Y I I D A V I 6 L P N M A S N Y Y V C W V L I E Y V Y 7
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ICL1 K Q L H ICL1ECL1 C W Y F ECL1ICL2 P L T Y P T K F ICL2ECL2 A N E E G I E E L V V A L T C V G G C Q A P L ECL2ICL3 A S S E S Y ICL3ECL3 N F I T ECL3N-term M T S D F S P E P P M E L C Y E N V N G S C I K N-termC-term G K V F R A D S S T T N L F S E E A G A G C-term S S Y A P W P R A I L Y G V L G L G A L L A V F G N L L V I I A I L H F T P T N F L V A S L A C A D F L V G V T V M P F S T V R S V E S G E S Y C K F H T C F D T S F C F A S L F H L C C I S I D R Y I A V T D T V S V S G L C I A L S W F F S V T Y S F S I F Y T G N Q N W V L L C F L L F F L P T V V M V F L Y G R I F L V A K Y Q A R K I E G T A N Q A Q K E R V A K R E R K A A K T L G I A M A A F L V S W L P Y I I D A V I D A Y M P A Y V Y E I L V W C V Y Y N S A M N P L I Y A F F Y P W I K L F R K A I V S
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Residue Table


GPCRdb(A)
GPCRdb(A)
TAAR9
TM3
3x29 3.29x29 T109
3x32 3.32x32 D112
3x33 3.33x33 T113
TM6
6x51 6.51x51 Y274
TM7
7x38 7.39x38 V297
7x41 7.42x41 V300
7x42 7.43x42 Y301