Structure information

mGlu2 receptor

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

8JCW

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

2

REFERENCE

10.1038/S41422-023-00830-2

PUBLICATION DATE

June 21, 2023

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
LY341495 R57 N-term polar (charge-assisted hydrogen bond)
LY341495 R61 N-term polar (charge-assisted hydrogen bond)
LY341495 S143 N-term polar (hydrogen bond with backbone)
LY341495 S143 N-term polar (hydrogen bond)
LY341495 S143 N-term polar (hydrogen bond)
LY341495 Y144 N-term Van der Waals
LY341495 S145 N-term polar (hydrogen bond)
LY341495 S145 N-term Van der Waals
LY341495 A166 N-term Van der Waals
LY341495 A166 N-term polar (hydrogen bond with backbone)
LY341495 S167 N-term Van der Waals
LY341495 T168 N-term Van der Waals
LY341495 T168 N-term polar (hydrogen bond)
LY341495 T168 N-term polar (hydrogen bond with backbone)
LY341495 D188 N-term Van der Waals
LY341495 Y216 N-term aromatic (face-to-face)
LY341495 Y216 N-term Van der Waals
LY341495 R271 N-term polar (charge-assisted hydrogen bond)
LY341495 K377 N-term polar (charge-assisted hydrogen bond)

Ligands

LY341495

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

L T A L A G L C A I T V P G V A W A D G 1 Y I L L G G V F L C Y C M T F I F I A 2 T L L A S Y C V S F A T G L G L R R L T 3 Q V A I C L A L I S G Q L L I V V A W L 4 A Y L T C L A I L L V N Y A L S G L M S 5 G F T M Y T T C I I W L A F L P I F Y V 6 G L V V S G S L S V S V C M T T T Q V R 7
Download: PNG | SVG
ICL1 T N A P V V K A S ICL1ECL1 K P ECL1ICL2 A R E G A Q R P R F I ICL2ECL2 A P G T G K E T A P E R R E V V T L R C N H R ECL2ICL3 P E N ICL3ECL3 S ECL3N-term M G S L L A L L A L L L L W G A V A E G P A K K V L T L E G D L V L G G L F P V H Q K G G P A E D C G P V N E H R G I Q R L E A M L F A L D R I N R D P H L L P G V R L G A H I L D S C S K D T H A L E Q A L D F V R A S L S R G A D G S R H I C P D G S Y A T H G D A P T A I T G V I G G S Y S D V S I Q V A N L L R L F Q I P Q I S Y A S T S A K L S D K S R Y D Y F A R T V P P D F F Q A K A M A E I L R F F N W T Y V S T V A S E G D Y G E T G I E A F E L E A R A R N I C V A T S E K V G R A M S R A A F E G V V R A L L Q K P S A R V A V L F T R S E D A R E L L A A S Q R L N A S F T W V A S D G W G A L E S V V A G S E G A A E G A I T I E L A S Y P I S D F A S Y F Q S L D P W N N S R N P W F R E F W E Q R F R C S F R Q R D C A A H S L R A V P F E Q E S K I M F V V N A V Y A M A H A L H N M H R A L C P N T T R L C D A M R P V N G R R L Y K D F V L N V K F D A P F R P A D T H N E V R F D R F G D G I G R Y N I F T Y L R A G S G R Y R Y Q K V G Y W A E G L T L D T S L I P W A S P S A G P L P A S R C S E P C L Q N E V K S V Q P G E V C C W L C I P C Q P Y E Y R L D E F T C A D C G L G Y W P N A S L T G C F E L P Q E Y I R W N-termC-term S R F G S A A A R A S S S L G Q G S G S Q F V P T V C N G R E V V D S T T S S L C-term G D A W A V G P V T I A C L G A L A T L F V L G V F V R H G R E L C Y I L L G G V F L C Y C M T F I F I A S T A V C T L R R L G L G T A F S V C Y S A L L T K T N R I A R I F G G S P A S Q V A I C L A L I S G Q L L I V V A W L V V E D A S M L G S L A Y N V L L I A L C T L Y A F K T R K C F N E A K F I G F T M Y T T C I I W L A F L P I F Y V T S D Y R V Q T T T M C V S V S L S G S V V L G C L F A P K L H I I L F Q P Q K H R A N V V S P T
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(C)
mGlu2 receptor