Structure information

succinate receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8JPP

SPECIES

Homo sapiens

RESOLUTION

3.200

PREFERRED CHAIN

R

REFERENCE

10.1038/S41422-024-00968-7

PUBLICATION DATE

May 22, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
succinic acid L79 2.60x60 TM2 hydrophobic
succinic acid F175 ECL2 polar (hydrogen bond with backbone)
succinic acid F175 ECL2 Van der Waals
succinic acid R281 7.39x38 TM7 polar (charge-assisted hydrogen bond)

Ligands

succinic acid

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Residue Diagrams

T N G L V G V V F E I G Y F I S L Y Y K 1 F N L S V S D L A F L C T L P M L I R S 2 F T L F L I S T Y L N A H L V Y R N S I 3 A I L I S L A I W V L V T L E L L P I 4 Y F F C M V F L P I L F G L L T L C M S Y 5 I M A V V I F S V L F T P Y H V M R N V 6 V P N I V S N L F A L P R T V I Y F S 7
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ICL1 K N W ICL1ECL1 G N W I Y ECL1ICL2 P F R E H L L Q ICL2ECL2 I T D N G T T C N D F A S S G ECL2ICL3 T A L P ICL3ECL3 S W K Q ECL3N-term M L G I M A W N A T N-termC-term T S F S R W A H E L L L S F R E K C-term C K N W L A A E A A L E K Y Y L S I F Y G I E F V V G V L G N T I V V Y G Y I F S L N S S N I Y L F N L S V S D L A F L C T L P M L I R S Y A N G D V L C I S N R Y V L H A N L Y T S I L F L T F I S I D R Y L I I K Y K K E F A I L I S L A I W V L V T L E L L P I L P L I N P V D P N Y N L I Y S M C L T L L G F L I P L F V M C F F Y Y K I A L F L K Q R N R Q V A L E K P L N L V I M A V V I F S V L F T P Y H V M R N V R I A S R L G Y Q C T Q V V I N S F Y I V T R P L A F L N S V I N P V F Y F L L G D H L M N N F K F R D M Q L R H S L
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Residue Table


GPCRdb(A)
GPCRdb(A)
succinate receptor
TM2
2x60 2.60x60 L79
TM7
7x38 7.39x38 R281