Structure information

OR1F1

PROTEIN CLASS

Class O2 (tetrapod specific odorant)

PDB CODE

8UXY

SPECIES

Homo sapiens

RESOLUTION

3.300

PREFERRED CHAIN

A

REFERENCE

10.1038/S41586-024-08126-0

PUBLICATION DATE

Oct. 30, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
l-Menthol F104 3.32x32 TM3 hydrophobic
l-Menthol N109 3.37x37 TM3 Van der Waals
l-Menthol N109 3.37x37 TM3 polar (hydrogen bond)
l-Menthol H159 4.60x60 TM4 Van der Waals
l-Menthol I199 5.39x39 TM5 Van der Waals
l-Menthol I207 5.47x47 TM5 hydrophobic
l-Menthol I207 5.47x47 TM5 Van der Waals
l-Menthol Y259 6.55x55 TM6 Van der Waals
l-Menthol Y259 6.55x55 TM6 hydrophobic

Ligands

l-Menthol

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Residue Diagrams

L N G L V T A L Y M S L F F V F L L H Q 1 S N L S F V D I C F S F T T V P K M L A 2 V A L L F N D M D V F M F V F Y M Q T L 3 C A L L V A G L W V V A N L N V L L H T 4 Y S A L I C L F P T I M V L A G E S L I 5 G S H L A V V L L F Y S T I I A V Y F 6 F P N L M P T V V T Y L V T A M T D K 7
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ICL1 S C L H ICL1ECL1 E T Q T I ECL1ICL2 P L H Y T A K M ICL2ECL2 P L S F C A D N A I T H F F C D V T P L L K L S C S D ECL2ICL3 V P ICL3ECL3 N P L S S H ECL3N-term M S G T N Q S S V S E F L L L G L S R N-termC-term V C-term Q P Q Q Q H L L F V F F L S M Y L A T V L G N L L I I L S V S I D T P M Y F F L S N L S F V D I C F S F T T V P K M L A N H I L S F C G C L T Q M Y F V F M F V D M D N F L L A V M A Y D H F V A V C H T H Q L C A L L V A G L W V V A N L N V L L H T L L M A T H L N E V I I L S E G A L V M I T P F L C I L A S Y M H I T C T V L K S T K G R W K A F S T C G S H L A V V L L F Y S T I I A V Y F S A E K D T M A T V L Y T V V T P M L N P F I Y S L R N R Y L K K V V F L K G A V V G R S
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Residue Table


GPCRdb(A)
GPCRdb(A)
OR1F1
TM3
3x32 3.32x32 V104
3x37 3.37x37 D109
TM4
4x60 4.60x60 H159
TM5
5x39 5.39x39 I199
5x47 5.47x47 M207
TM6
6x55 6.55x55 Y259