PDB
8UY0
Resolution
3.2 Å
Released
Oct. 30, 2024
Receptor
OR2T2
Class
O2
Species
Homo sapiens
Ligand
Function
S-carvone
Agonist
Reference
10.1038/S41586-024-08126-0

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
S-carvone Y103 3.32x32 TM3 hydrophobic
S-carvone L104 3.33x33 TM3 hydrophobic
S-carvone G107 3.36x36 TM3 Van der Waals
S-carvone G108 3.37x37 TM3 Van der Waals
S-carvone C111 3.40x40 TM3 Van der Waals
S-carvone D154 4.56x56 TM4 Van der Waals
S-carvone M198 5.39x39 TM5 hydrophobic
S-carvone C201 5.42x42 TM5 Van der Waals
S-carvone C202 5.43x43 TM5 Van der Waals
S-carvone F250 6.47x47 TM6 hydrophobic
S-carvone Y258 ECL3 hydrophobic
S-carvone Y277 7.41x40 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 S R L H ICL1ECL1 K D K T I ECL1ICL2 P L R Y P L L M ICL2ECL2 P F C R S R E I N H F F C E I P A V L K L S C T D ECL2ICL3 M N ICL3ECL3 P H S Y H ECL3N-term M G M E G L L Q N S T N F V L T G L I T H P A N-termC-term K G C-term F P G L L F A I V F S I F V V A I T A N L V M I L L I H M D T P M Y F L L S Q L S I M D T I Y I C I T V P K M L Q D L L S S F L G C A V Q I F L Y L T L I G G E F F L L G L M A Y D R Y V A V C N N R R V C L F M V V G S W V G G S L D G F M L T P V T M S F T S L Y E T L M Y A C C V L M L L I P L S V I S V S Y T H I L L T V H R S A E G R R K A F A T C S S H I M V V S V F Y G A A F Y T N V L T P E K D K V V S A F Y T I L T P M L N P L I Y S L R N K D L R K C G S R V A V A A A V L G R S Q S I T V I R
Helix box plot — Download: PNG | SVG L N A T I A V V F I S F V I A F L L G P 1 S Q L S I M D T I Y I C I T V P K M L Q 2 L G L L F F E G G I L T L Y L F I Q V A 3 C L F M V V G S W V G G S L D G F M L T 4 Y S V S I V S L P I L L M L V C C A Y M 5 S S H I M V V S V F Y G A A F Y T N V L 6 L P N L M P T L I T Y F A S V V K D K 7

GPCRdb(A)
GPCRdb(A)
OR2T2
TM3
3x32 3.32x32 Y105
3x33 3.33x33 L106
3x36 3.36x36 I109
3x37 3.37x37 G110
3x40 3.40x40 F113
TM4
4x56 4.56x56 D156
TM5
5x39 5.39x39 M200
5x42 5.42x42 C203
5x43 5.43x43 C204
TM6
6x47 6.47x47 F252
TM7
7x40 7.41x40 Y279