PDB
8Y01
Resolution
2.5 Å
Released
Feb. 12, 2025
Receptor
OPN1MW
Class
A
Species
Homo sapiens
Ligand
all-trans-retinal
Function
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
all-trans-retinal V133 3.32x32 TM3 hydrophobic
all-trans-retinal L223 5.42x43 TM5 hydrophobic
all-trans-retinal M224 5.43x44 TM5 hydrophobic
all-trans-retinal C227 5.46x461 TM5 hydrophobic
all-trans-retinal C228 5.47x47 TM5 hydrophobic
all-trans-retinal W281 6.48x48 TM6 hydrophobic
all-trans-retinal Y284 6.51x51 TM6 hydrophobic
all-trans-retinal A285 6.52x52 TM6 hydrophobic
all-trans-retinal A288 6.55x55 TM6 hydrophobic
all-trans-retinal A311 7.42x41 TM7 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 K K L R ICL1ECL1 Y F V L ECL1ICL2 P F G N V R F ICL2ECL2 W S R Y W P H G L K T S C G P D V F S G S S Y P ECL2ICL3 E ICL3ECL3 G Y P F ECL3N-term M A Q Q W S L Q R L A G R H P Q D S Y E D S T Q S S I F T Y T N S N S T R G P F E G P N Y H I A N-termC-term K K V D D G S E L S S A S K T E V S S V S S V S P A C-term P R W V Y H L T S V W M I F V V I A S V F T N G L V L A A T M K F H P L N W I L V N L A V A D L A E T V I A S T I S V V N Q V Y G G H P M C V L E G Y T V S L C G I T G L W S L A I I S W E R W M V V C K D A K L A I V G I A F S W I W A A V W T A P P I F G G V Q S Y M I V L M V T C C I T P L S I I V L C Y L Q V W L A I R A V A K Q Q K S E S T Q K A E K E V T R M V V V M V L A F C F C W G P Y A F F A C F A A A N P H P L M A A L P A F F A K S A T I Y N P V I Y V F M N R Q I L Q F R N C L F G
Helix box plot — Download: PNG | SVG G N T F V S A I V V F I M W V S T L H Y 1 V N L A V A D L A E T I V A S T I S V V N 2 I A L S W L G T I G C L S V T Y G E L V 3 A I V G I A F S W I W A A V W T A P P I 4 Y C L V I I S L P T I C C T V M L V I M Y 5 V V M V L A F C F C W G P Y A F F A C F 6 V P N Y I T A S K A F F A P L A A M L 7

GPCRdb(A)
GPCRdb(A)
OPN1MW
TM3
3x32 3.32x32 V133
TM5
5x43 5.42x43 L223
5x44 5.43x44 M224
5x461 5.46x461 C227
5x47 5.47x47 C228
TM6
6x48 6.48x48 W281
6x51 6.51x51 Y284
6x52 6.52x52 A285
6x55 6.55x55 A288
TM7
7x41 7.42x41 A311