Structure information

H2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8YUT

SPECIES

Homo sapiens

RESOLUTION

2.700

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

June 5, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
amthamine D98 3.32x32 TM3 polar (charge-assisted hydrogen bond)
amthamine V99 3.33x33 TM3 hydrophobic
amthamine V99 3.33x33 TM3 Van der Waals
amthamine C102 3.36x36 TM3 Van der Waals
amthamine T103 3.37x37 TM3 polar (hydrogen bond)
amthamine D186 5.42x43 TM5 polar (charge-assisted hydrogen bond)
amthamine T190 5.46x461 TM5 polar (hydrogen bond)
amthamine Y250 6.51x51 TM6 polar (hydrogen bond)
amthamine F251 6.52x52 TM6 Van der Waals
amthamine F254 6.55x55 TM6 hydrophobic
amthamine F254 6.55x55 TM6 Van der Waals

Ligands

amthamine

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Residue Diagrams

V N G A V T I L I L V A L V V T I T I K 1 V S L A I T D L L L G L L V L P F S A I Y 2 M F L N L I S A T C L M V D L S T Y I N 3 V A I S L V L I W V I S I T L S F L S I 4 Y T I C M I L L P L Y F T V L G D V L G Y 5 A A V M G A F I I C W F P Y F T A F V Y 6 I P N L A S N A Y G L W L V I A E L V 7
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ICL1 R R L R ICL1ECL1 K W S F ECL1ICL2 P L R Y P V L V ICL2ECL2 W N S R N E T S K G N H T T S K C K V Q V ECL2ICL3 H I S ICL3ECL3 G D D A I ECL3N-term M A P N G T A S S N-termC-term C R L A N R N S H K T S L R S N A S Q L S R T Q S R E P R Q Q E E K P L K L Q V W S G T E V T A P Q G A T D R C-term F C L D S T A C K I T I T V V L A V L I L I T V A G N V V V C L A V G L N N L T N C F I V S L A I T D L L L G L L V L P F S A I Y Q L S C G K V F C N I Y T S L D V M L C T A S I L N L F M I S L D R Y C A V M D T P V R V A I S L V L I W V I S I T L S F L S I H L G N E V Y G L V D G L V T F Y L P L L I M C I T Y Y R I F K V A R D Q A K R I N S W K A A T I R E H K A T V T L A A V M G A F I I C W F P Y F T A F V Y R G L R N E V L E A I V L W L G Y A N S A L N P I L Y A A L N R D Y Q Q F R T G L F C
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Residue Table


GPCRdb(A)
GPCRdb(A)
H2 receptor
TM3
3x32 3.32x32 D98
3x33 3.33x33 V99
3x36 3.36x36 C102
3x37 3.37x37 T103
TM5
5x43 5.42x43 D186
5x461 5.46x461 T190
TM6
6x51 6.51x51 Y250
6x52 6.52x52 F251
6x55 6.55x55 F254