Structure information

TA1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8ZSV

SPECIES

Mus musculus

RESOLUTION

2.960

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

July 24, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
RO5256390 D102 3.32x32 TM3 polar (charge-assisted hydrogen bond)
RO5256390 I103 3.33x33 TM3 hydrophobic
RO5256390 I103 3.33x33 TM3 Van der Waals
RO5256390 S106 3.36x36 TM3 polar (hydrogen bond)
RO5256390 P183 45.52x52 ECL2 Van der Waals
RO5256390 F185 ECL2 hydrophobic
RO5256390 F185 ECL2 Van der Waals
RO5256390 W261 6.48x48 TM6 hydrophobic
RO5256390 W261 6.48x48 TM6 Van der Waals
RO5256390 F264 6.51x51 TM6 Van der Waals
RO5256390 F264 6.51x51 TM6 hydrophobic
RO5256390 F265 6.52x52 TM6 hydrophobic
RO5256390 F265 6.52x52 TM6 Van der Waals
RO5256390 Y287 7.39x38 TM7 polar (hydrogen bond with backbone)
RO5256390 Y287 7.39x38 TM7 Van der Waals
RO5256390 G290 7.42x41 TM7 Van der Waals

Ligands

RO5256390

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Residue Diagrams

L N G V L T A L I I L S M L S Y L S A Q 1 H S M A I V D F L L G L C I M P C S M V R 2 F A L H F I S A S S L M I D T S T H V K 3 I L V M I L V S W S L P A V Y A F G M I 4 Y V F L M V S G P I Y F S T M F A L V G S 5 G I M V G V F L V C W C P F F L C T V L 6 M P N L A S N L Y G F W Y L A D N L S 7
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ICL1 K Q L H ICL1ECL1 C W Y F ECL1ICL2 P L R Y K A K I ICL2ECL2 L N L K G V E E L Y R S Q V S D L G G C S P F F ECL2ICL3 L E G K S Q ICL3ECL3 Y V I ECL3N-term M H L C H A I T N I S H R N S D W S R E N-termC-term G K I F Q K D S S R S K L F L C-term V Q A S L Y S L M S L I I L A T L V G N L I V I I S I S H F T P T N W L L H S M A I V D F L L G C L I M P C S M V R T V E R G E I L C K V H T S T D I M L S S A S I F H L A F I S I D R Y C A V C D N I S T I L V M I L V S W S L P A V Y A F G M I F L E S K V S G V L A F M T S F Y I P G S V M L F V Y Y R I Y F I A K G Q A R S I N R T N V Q V G A P Q S K E T K A A K T L G I M V G V F L V C W C P F F L C T V L D P F L G P P S L N D A L Y W F G Y L N S A L N P M V Y A F F Y P W L K M F R R A V L L
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Residue Table


GPCRdb(A)
GPCRdb(A)
TA1 receptor
TM3
3x32 3.32x32 D102
3x33 3.33x33 I103
3x36 3.36x36 S106
ECL2
45x52 45.52x52 P183
TM6
6x48 6.48x48 W261
6x51 6.51x51 F264
6x52 6.52x52 F265
TM7
7x38 7.39x38 Y287
7x41 7.42x41 G290