PDB
9AU0
Resolution
2.5 Å
Released
Aug. 27, 2025
Receptor
DP1
Class
A
Species
Homo sapiens
Ligand
CHEMBL1591294
Function
Agonist
Reference
—

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL1591294 G23 1.39x39 TM1 Van der Waals
CHEMBL1591294 G23 1.39x39 TM1 polar (hydrogen bond with backbone)
CHEMBL1591294 L26 1.42x42 TM1 Van der Waals
CHEMBL1591294 F27 1.43x43 TM1 Van der Waals
CHEMBL1591294 K76 2.54x54 TM2 polar (charge-assisted hydrogen bond)
CHEMBL1591294 L79 2.57x57 TM2 hydrophobic
CHEMBL1591294 S80 2.58x58 TM2 polar (hydrogen bond)
CHEMBL1591294 V83 2.61x61 TM2 Van der Waals
CHEMBL1591294 V83 2.61x61 TM2 hydrophobic
CHEMBL1591294 Y87 2.65x65 TM2 polar (hydrogen bond)
CHEMBL1591294 Y87 2.65x65 TM2 Van der Waals
CHEMBL1591294 M112 3.32x32 TM3 hydrophobic
CHEMBL1591294 M112 3.32x32 TM3 Van der Waals
CHEMBL1591294 F115 3.35x35 TM3 Van der Waals
CHEMBL1591294 F115 3.35x35 TM3 hydrophobic
CHEMBL1591294 G116 3.36x36 TM3 Van der Waals
CHEMBL1591294 T181 ECL2 Van der Waals
CHEMBL1591294 T181 ECL2 polar (hydrogen bond)
CHEMBL1591294 W182 ECL2 Van der Waals
CHEMBL1591294 W182 ECL2 hydrophobic
CHEMBL1591294 L306 7.36x35 TM7 hydrophobic
CHEMBL1591294 R310 7.40x39 TM7 polar (charge-assisted hydrogen bond)
CHEMBL1591294 L312 7.42x41 TM7 hydrophobic
CHEMBL1591294 L312 7.42x41 TM7 Van der Waals
CHEMBL1591294 S313 7.43x42 TM7 Van der Waals
CHEMBL1591294 S316 7.46x46 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 G L G W C S R R P L R P L P ICL1ECL1 R S L R V L A ECL1ICL2 P F F Y R R H I ICL2ECL2 F G K F V Q Y C P G T W C F I Q M V H E E G S L S V ECL2ICL3 C A E P R A D G R E ICL3ECL3 D V K E K N ECL3N-term M K S P F Y R C Q N T T S V E K G N N-termC-term R P L R Y R S R C S N S T N M E S S L C-term S A V M G G V L F S T G L L G N L L A L G L L A R S S V F Y M L V C G L T V T D L L G K C L L S P V V L A A Y A Q N P A L D N S L C Q A F A F F M S F F G L S S T L Q L L A M A L E C W L S L G H T L R L G A L V A P V V S A F S L A F C A L P F M G L G Y S V L Y S S L M A L L V L A T V L C N L G A M R N L Y A M H R R L Q R H P R S C T R D A S P Q P L E E L D H L L L L A L M T V L F T M C S L P V I Y R A Y Y G A F K R T S E E A E D L R A L R F L S V I S I V D P W I F I I F R S P F F H V F R I K I F I
Helix box plot — Download: PNG | SVG L N G L L G T S F L V G G M V A S 1 C G L T V T D L L G K C L L S P V V L A 2 A L L Q L T S S L G F F S M F F A F A Q 3 G A L V A P V V S A F S L A F C A L P F 4 G L N C L V T A L V L L A M L S S Y L V 5 A L M T V L F T M C S L P V I Y R A Y Y 6 W P D V I S I V S L F R L A R L D E A 7

GPCRdb(A)
GPCRdb(A)
DP1 receptor
TM1
1x39 1.39x39 G23
1x42 1.42x42 L26
1x43 1.43x43 F27
TM2
2x54 2.54x54 K76
2x57 2.57x57 L79
2x58 2.58x58 S80
2x61 2.61x61 V83
2x65 2.65x65 Y87
TM3
3x32 3.32x32 M112
3x35 3.35x35 F115
3x36 3.36x36 G116
TM7
7x35 7.36x35 L306
7x39 7.40x39 R310
7x41 7.42x41 L312
7x42 7.43x42 S313
7x46 7.46x46 S316