PDB
9BSB
Resolution
2.3 Å
Released
Sept. 17, 2025
Receptor
D2
Class
A
Species
Homo sapiens
Ligand
(+)-LSD
Function
Agonist
Reference
10.1016/J.NEURON.2025.06.012

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
(+)-LSD F110 3.28x28 TM3 hydrophobic
(+)-LSD V111 3.29x29 TM3 hydrophobic
(+)-LSD D114 3.32x32 TM3 polar (charge-assisted hydrogen bond)
(+)-LSD V115 3.33x33 TM3 Van der Waals
(+)-LSD V115 3.33x33 TM3 hydrophobic
(+)-LSD C118 3.36x36 TM3 hydrophobic
(+)-LSD C118 3.36x36 TM3 Van der Waals
(+)-LSD T119 3.37x37 TM3 Van der Waals
(+)-LSD S193 5.42x43 TM5 Van der Waals
(+)-LSD S194 5.43x44 TM5 Van der Waals
(+)-LSD S197 5.46x461 TM5 polar (hydrogen bond)
(+)-LSD S197 5.46x461 TM5 Van der Waals
(+)-LSD W386 6.48x48 TM6 hydrophobic
(+)-LSD F389 6.51x51 TM6 hydrophobic
(+)-LSD F389 6.51x51 TM6 Van der Waals
(+)-LSD F390 6.52x52 TM6 aromatic (edge-to-face)
(+)-LSD F390 6.52x52 TM6 Van der Waals
(+)-LSD H393 6.55x55 TM6 Van der Waals
(+)-LSD T412 7.39x38 TM7 Van der Waals
(+)-LSD Y416 7.43x42 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 K A L Q ICL1ECL1 E W K F ECL1ICL2 P M L Y N ICL2ECL2 L N N A D Q N E C I I A ECL2ICL3 R S S R A F R A H L R A P L K G N C T H P E D M K L C T V I M K S N G S F P V N R R R V E A A R R A Q E L E M E M L S S T S P P E R T R Y S P I P P S H H Q L T L P D P S H H G L H S T P D S P A K P E K N G H A K D H P K I A K I F E I Q T M P N G K T R T S L K T M S R R ICL3ECL3 D C N I ECL3N-term M D P L N L S W Y D D D L E R Q N W S R P F N G S D G K A D N-termC-term C C-term R P H Y N Y Y A T L L T L L I A V I V F G N V L V C M A V S R E T T T N Y L I V S L A V A D L L V A T L V M P W V V Y L E V V G S R I H C D I F V T L D V M M C T A S I L N L C A I S I D R Y T A V A M T R Y S S K R R V T V M I S I V W V L S F T I S C P L L F G N P A F V V Y S S I V S F Y V P F I V T L L V Y I K I Y I V L R R R R K R V N T K K L S Q Q K E K K A T Q M L A I V L G V F I I C W L P F F I T H I L N I H C P P V L Y S A F T W L G Y V N S A V N P I I Y T T F N I E F L K F R K A I L H
Helix box plot — Download: PNG | SVG V N G F V I V A I L L T L L T A Y Y N Y 1 V S L A V A D L L V A L T V M P W V V Y L 2 A C L N L I S A T C M M V D L T V F I D 3 V T V M I S I V W V L S F T I S C P L 4 Y V L L T V I F P V Y F S V I S S Y V V F 5 A I V L G V F I I C W L P F F I T H I L 6 I P N V A S N V Y G L W T F A S Y L V 7

GPCRdb(A)
GPCRdb(A)
D2 receptor
TM3
3x28 3.28x28 F110
3x29 3.29x29 V111
3x32 3.32x32 D114
3x33 3.33x33 V115
3x36 3.36x36 C118
3x37 3.37x37 T119
TM5
5x43 5.42x43 S193
5x44 5.43x44 S194
5x461 5.46x461 S197
TM6
6x48 6.48x48 W386
6x51 6.51x51 F389
6x52 6.52x52 F390
6x55 6.55x55 H393
TM7
7x38 7.39x38 T412
7x42 7.43x42 Y416