PDB
9KZK
Resolution
3.5 Å
Released
Nov. 26, 2025
Receptor
C3a
Class
A
Species
Mus musculus
Ligand
mouse C3a anaphylatoxin
Function
Agonist
Reference
10.1101/2025.05.26.656101

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
mouse C3a anaphylatoxin P99 3.29x29 TM3 hydrophobic
mouse C3a anaphylatoxin I103 3.33x33 TM3 hydrophobic
mouse C3a anaphylatoxin Y174 45.52x52 ECL2 polar (hydrogen bond)
mouse C3a anaphylatoxin R333 5.42x43 TM5 polar (charge-assisted hydrogen bond)
mouse C3a anaphylatoxin Y386 6.51x51 TM6 polar (hydrogen bond)
mouse C3a anaphylatoxin Y386 6.51x51 TM6 polar (hydrogen bond)
mouse C3a anaphylatoxin E404 7.29x28 TM7 polar (charge-assisted hydrogen bond)
mouse C3a anaphylatoxin D410 7.35x34 TM7 polar (charge-assisted hydrogen bond)
mouse C3a anaphylatoxin H411 7.36x35 TM7 Van der Waals
mouse C3a anaphylatoxin I414 7.39x38 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 M K T ICL1ECL1 G H W P Y ECL1ICL2 P I W C Q N H R ICL2ECL2 D L F I M D N R S I C R Y N F D S S R S Y D Y W D Y V Y K L S L P E S N S T D N S T A Q L T G H M N D R S A P S S V Q A R D Y F W T V T T A L Q S Q P F L T S P E D S F S L D S A N Q Q P H Y G G K P P N V L T A A V P S G F P V E D R K S N T L N A D A F L S A H T E L F P T A S S G H L Y P Y D F Q G D Y V D Q F T Y D N H ECL2ICL3 T N F T K S R ICL3ECL3 D P E ECL3N-term M E S F D A D T N S T D L H S R P L F N-termC-term S I K G I L E A A F S E E L T H S T N C T Q D K A S S K R N N M S T D V C-term Q P Q D I A S M V I L G L T C L L G L L G N G L V L W V A G V K T V N T V W F L H L T L A D F L C C L S L P F S L A H L I L Q G L F L C K L I P S I I I L N M F A S V F L L T A I S L D R C L I V H K N V R T A F A I C G C V W V V A F V M C V P V F V Y R V P T P L M A I T I T R L V V G F L V P F F I M V I C Y S L I V F R M R K N K T F R V A V A V V T V F F I C W T P Y H L V G V L L L I T S S L G E A V M S W D H M S I A L A S A N S C F N P F L Y A L L G K D A R Q F R K K
Helix box plot — Download: PNG | SVG G N G L L G L L C T L G L I V M S A I D 1 L H L T L A D F L C C L S L P F S L A H 2 A T L L F V S A F M N L I I I S P I L K 3 A F A I C G C V W V V A F V M C V P V 4 Y C I V M I F F P V L F G V V L R T I T I 5 V A V V T V F F I C W T P Y H L V G V L 6 F P N F C S N A S A L A I S M H D W S 7

GPCRdb(A)
GPCRdb(A)
C3a receptor
TM3
3x29 3.29x29 P99
3x33 3.33x33 I103
ECL2
45x52 45.52x52 Y174
TM5
5x43 5.42x43 R333
TM6
6x51 6.51x51 Y386
TM7
7x28 7.29x28 E404
7x34 7.35x34 D410
7x35 7.36x35 H411
7x38 7.39x38 I414