PDB
9UAM
Resolution
3.3 Å
Released
March 18, 2026
Receptor
CysLT2
Class
A
Species
Homo sapiens
Ligand
LTC4
Function
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
LTC4 F137 3.51x51 TM3 hydrophobic
LTC4 H142 3.56x56 TM3 polar (hydrogen bond)
LTC4 H142 3.56x56 TM3 Van der Waals
LTC4 L147 ICL2 Van der Waals
LTC4 I219 5.56x56 TM5 hydrophobic
LTC4 I219 5.56x56 TM5 Van der Waals

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Snake plot — Download: PNG | SVG
ICL1 Y K K S ICL1ECL1 S N W I F ECL1ICL2 P F R L L H V T ICL2ECL2 G S E Q N G S V T S C L E L N L Y K ECL2ICL3 E V P E ICL3ECL3 K V G L C ECL3N-term M E R K F M S L Q P S I S V S E M E P N G T F S N N N S R N N-termC-term G H P Q K A K T K C V F P V S V W L R K E T R V C-term C T I E N F K R E F F P I V Y L I I F F W G V L G N G L S I Y V F L Q P T S V N V F M L N L A I S D L L F I S T L P F R A D Y Y L R G G D L A C R I M S Y S L Y V N M Y S S I Y F L T V L S V V R F L A M V H S I R S A W I L C G I I W I L I M A S S I M L L D S I A K L Q T M N Y I A L V V G C L L P F F T L S I C Y L L I I R V L L K V S G L R V S H R K A L T T I I I T L I I F F L C F L P Y H T L R T V H L T T W K D R L H K A L V I T L A L A A A N A C F N P L L Y Y F A G E N L K S F K D R A L R K
Helix box plot — Download: PNG | SVG G N G L V G W F F I I L Y V I P F F E R 1 L N L A I S D L L F I S T L P F R A D Y 2 V T L F Y I S S Y M N V Y L S Y S M I R 3 A W I L C G I I W I L I M A S S I M L 4 Y C I S L T F F P L L C G V V L A I Y N M 5 I I I T L I I F L F C F L P Y H T L R T V 6 L P N F C A N A A A L A L T I V L A K 7

GPCRdb(A)
GPCRdb(A)
CysLT2 receptor
TM3
3x51 3.51x51 F137
3x56 3.56x56 H142
TM5
5x56 5.56x56 I219