PDB
9WIK
Resolution
3.3 Å
Released
July 1, 2026
Receptor
GPR84
Class
A
Species
Homo sapiens
Ligand
DL-175
Function
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
DL-175 L100 3.32x32 TM3 hydrophobic
DL-175 F101 3.33x33 TM3 hydrophobic
DL-175 F152 4.57x57 TM4 hydrophobic
DL-175 M183 5.43x44 TM5 hydrophobic
DL-175 Y186 5.46x461 TM5 hydrophobic
DL-175 F187 5.47x47 TM5 hydrophobic
DL-175 F335 6.51x51 TM6 hydrophobic
DL-175 L336 6.52x52 TM6 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 P K L R ICL1ECL1 L H W R T ECL1ICL2 P K L F P Q V F ICL2ECL2 I L V P V V C T C S F D R I R ECL2ICL3 L R Q A S I H S N H V A R T D E A M P G R F Q E L D S R L A S G G P S E G I S S E P V S A A T T Q T L E G D S S E V G D Q I N S K R A K Q M A E K S P P E A S A K A Q P I K G A R R A ICL3ECL3 R V Q A P R ECL3N-term M W N S S D A N F S C Y H E S V L N-termC-term G P R S F H R L H C-term G Y R Y V A V S W G V V V A V T G T V G N V L T L L A L A I Q T R F N L L I A N L T L A D L L Y C T L L Q P F S V D T Y L H G A T F C R V F G L L L F A S N S V S I L T L C L I A L G R Y L L I A H S A K G I V L A L V S T W V V G V A S F A P L W P I Y G R P Y T T I L M G I Y F V L G L S S V G I F Y C L I H R Q V K R A A Q A L D Q Y K P D S S S E F G K V T R M C F A V F L C F A L S Y I P F L L L N I L D A V V H M L A A N L T W L N G C I N P V L Y A A M N R Q Y G S F R Q A I L K R
Helix box plot — Download: PNG | SVG V N G V T G T V A V V V G W S V A V Y R 1 A N L T L A D L L Y C L T L Q P F S V D T 2 L C L T L I S V S N S A F L L L G F V R 3 I V L A L V S T W V V G V A S F A P L 4 Y F I G V S S L G L V F Y I G M L I T T Y 5 F A V F L C F A L S Y I P F L L L N I L 6 V P N I C G N L W T L N A A L M H V V 7

GPCRdb(A)
GPCRdb(A)
GPR84
TM3
3x32 3.32x32 L100
3x33 3.33x33 F101
TM4
4x57 4.57x57 F152
TM5
5x44 5.43x44 M183
5x461 5.46x461 Y186
5x47 5.47x47 F187
TM6
6x51 6.51x51 F335
6x52 6.52x52 L336