PDB
9YDV
Resolution
3.1 Å
Released
Nov. 19, 2025
Receptor
P2Y14
Class
A
Species
Homo sapiens
Ligand
CHEMBL1198696
Function
Agonist
Reference
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Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL1198696 Y102 3.33x33 TM3 aromatic (face-to-face)
CHEMBL1198696 H184 5.36x36 TM5 polar (hydrogen bond)
CHEMBL1198696 H184 5.36x36 TM5 Van der Waals
CHEMBL1198696 F191 5.43x43 TM5 Van der Waals
CHEMBL1198696 R253 6.55x55 TM6 Van der Waals
CHEMBL1198696 Y256 6.58x58 TM6 polar (hydrogen bond)
CHEMBL1198696 Y256 6.58x58 TM6 Van der Waals
CHEMBL1198696 Q260 6.62x62 TM6 polar (hydrogen bond)
CHEMBL1198696 Q260 6.62x62 TM6 Van der Waals
CHEMBL1198696 R274 7.32x31 TM7 Van der Waals
CHEMBL1198696 K277 7.35x34 TM7 Van der Waals

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Snake plot — Download: PNG | SVG
ICL1 P S S ICL1ECL1 L G P ECL1ICL2 P L W T S F I Q ICL2ECL2 N Q S V R E V T Q I K C I E L K S ECL2ICL3 L K S ICL3ECL3 A H Y ECL3N-term M I N S T S T Q P P D E S C S Q N N-termC-term L H I P L K A Q N D L D I S R I K R G N T T L E S T D T L C-term L L I T Q Q I I P V L Y C M V F I A G I L L N G V S G W I F F Y V K S F I I Y L K N I V I A D F V M S L T F P F K I L G D S G W Q L N V F V C R V S A V L F Y V N M Y V S I V F F G L I S F D R Y Y K I V K S V S Y S K L L S V I V W M L M L L L A V P N I I L T E L G R K W H K A S N Y I F V A I F W I V F L L L I V F Y T A I T K K I F K S H S R N S T S V K K K S S R N I F S I V F V F F V C F V P Y H I A R I P Y T K S Q T E S C Q S K E I L R Y M K E F T L L L S A A N V C L D P I I Y F F L C Q P L C K F R E I K
Helix box plot — Download: PNG | SVG G N L L I G A I F V M C Y L V P I I Q Q 1 K N I V I A D F V M S L T F P F K I L G 2 L G F F V I S V Y M N V Y F L V A S V R 3 S K L L S V I V W M L M L L L A V P N I 4 Y F V I L L L F V I W F I A V F I Y N S 5 I F S I V F V F V F C F V P Y H I A R I P 6 I P D L C V N A A S L L L T F E K M Y 7

GPCRdb(A)
GPCRdb(A)
P2Y14 receptor
TM3
3x33 3.33x33 Y102
TM5
5x36 5.36x36 H184
5x43 5.43x43 F191
TM6
6x55 6.55x55 R253
6x58 6.58x58 Y256
6x62 6.62x62 Q260
TM7
7x31 7.32x31 R274
7x34 7.35x34 K277