CHEMBL246598


SMILES CCN1C(=O)COc2ccc(CC3CCN(CCOc4cccc5nc(C)ccc45)CC3)cc21
InChIKey AVSPJTOPUUMEGQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 459.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.5 9.05 9.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database