CHEMBL249854


SMILES CC(=O)c1sc(NC(=O)N[C@@H]2CN(C(C)=O)CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C
InChIKey ZFRLEPMXXGKKBN-WPFOTENUSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 529.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Mouse Chemokine A pIC50 8.15 8.29 8.44 ChEMBL
CCR3 CCR3 Human Chemokine A pIC50 8.59 9.16 10.17 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.28 5.28 5.28 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.19 6.19 6.19 ChEMBL