CHEMBL252816


SMILES O=C(NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21)C(F)(F)F
InChIKey ZUJPXZIUFHGAJI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Rat Adrenoceptors A pKi 8.72 8.72 8.72 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.31 8.31 8.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.31 8.31 8.31 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 8.0 8.0 8.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database