CHEMBL3040288
SMILES | Fc1cccc(Nc2nc(Cc3ccccc3)nc3c2CCNCC3)c1 |
InChIKey | DUMBRKXSQQUMRX-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 2 |
Rotatable bonds | 4 |
Molecular weight (Da) | 348.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pIC50 | 5.97 | 5.97 | 5.97 | ChEMBL |
5-HT6 | 5HT6R | Human | 5-Hydroxytryptamine | A | pIC50 | 7.65 | 7.65 | 7.65 | ChEMBL |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pIC50 | 7.88 | 7.88 | 7.88 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pIC50 | 6.17 | 6.17 | 6.17 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pIC50 | 8.31 | 8.31 | 8.31 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pEC50 | 7.55 | 7.55 | 7.55 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pIC50 | 5.9 | 5.9 | 5.9 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pIC50 | 7.2 | 7.2 | 7.2 | ChEMBL |