GPCRdb

CLOTHIAPINE

Agent/drug
Bioactivity

CLOTHIAPINE

SMILES	CN1CCN(C2=Nc3ccccc3Sc3ccc(Cl)cc32)CC1
InChIKey	KAAZGXDPUNNEFN-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	0
Molecular weight (Da)	343.1

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

CLOTHIAPINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 4

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease

Gene	Protein	Receptor family	Ligand type	Class	Name	Phase	ICD11	ATC	Association score

5HT2A	5-HT_2A receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Schizophrenia or other primary psychotic disorders, unspecified	4	6A2Z		0.609
5HT2B	5-HT_2B receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Schizophrenia or other primary psychotic disorders, unspecified	4	6A2Z		0.463
5HT2C	5-HT_2C receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Schizophrenia or other primary psychotic disorders, unspecified	4	6A2Z		0.589
DRD4	D₄ receptor	Dopamine receptors	Aminergic receptors	A	Schizophrenia or other primary psychotic disorders, unspecified	4	6A2Z		0.583

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