sonepiprazole


SMILES NS(=O)(=O)c1ccc(cc1)N1CCN(CC1)CC[C@@H]1OCCc2c1cccc2
InChIKey WNUQCGWXPNGORO-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.9 8.9 8.9 Guide to Pharmacology
D4 DRD4 Rat Dopamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
D4 DRD4 Human Dopamine A pKi 8.17 8.3 8.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.29 5.29 5.29 ChEMBL
D4 DRD4 Rat Dopamine A pKi 8.14 8.14 8.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database