CHEMBL270406


SMILES COc1cc(CN2CCN(c3ccccc3OC)CC2)c(OCCF)cc1OC
InChIKey KPFBQVMYZMGXQK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.17 5.17 5.17 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.03 7.03 7.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database