SR2640


SMILES OC(=O)c1ccccc1Nc1cccc(c1)OCc1ccc2c(n1)cccc2
InChIKey LMPZHLXYBWGGNT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 370.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT1 CLTR1 Human Leukotriene A pKi 8.7 8.7 8.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT1 CLTR1 Guinea pig Leukotriene A pIC50 7.64 7.64 7.64 ChEMBL
CysLT1 CLTR1 Human Leukotriene A pIC50 7.64 7.64 7.64 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.5 4.5 4.5 ChEMBL