tasosartan


SMILES Cc1nc(C)c2c(n1)N(Cc1ccc(cc1)c1ccccc1c1nn[nH]n1)C(=O)CC2
InChIKey ADXGNEYLLLSOAR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pIC50 8.92 8.92 8.92 Guide to Pharmacology
AT1 AGTR1 Human Angiotensin A pIC50 7.42 7.46 7.5 ChEMBL
AT1 AGTR1 Human Angiotensin A pIC50 8.13 8.13 8.13 Drug Central