CHEMBL313851


SMILES FC(F)(F)c1nc2c3c(ccc2[nH]1)CCC(CNCc1ccccc1)O3
InChIKey JFFIIIVILGKQSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 361.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.19 7.71 8.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.88 6.88 6.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database