ELTOPRAZINE


SMILES c1cc2c(c(N3CCNCC3)c1)OCCO2
InChIKey WVLHGCRWEHCIOT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 220.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 7.27 7.27 7.27 ChEMBL
β1 ADRB1 Human Adrenoceptors A pKd 4.8 4.8 4.8 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.4 7.5 8.03 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.4 7.71 8.03 PDSP Ki database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 7.27 7.28 7.28 PDSP Ki database
5-HT2C K7GSR7 Pig 5-Hydroxytryptamine A pKi 6.77 6.93 7.09 PDSP Ki database
δ OPRD Rat Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
CCK2 GASR Rat Cholecystokinin A pKi 5.0 5.0 5.0 PDSP Ki database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Rat Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 5.41 5.41 5.41 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 5.96 5.96 5.96 PDSP Ki database
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 5.0 5.0 5.0 PDSP Ki database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1D F1MMU1 Bovine 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 PDSP Ki database
μ OPRM Rat Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database