AXELOPRAN


SMILES NC(=O)c1cccc([C@@H]2C[C@@H]3CC[C@H](C2)N3CCN(CC2CCCCC2)C(=O)[C@@H](O)CO)c1
InChIKey ATLYLVPZNWDJBW-KIHHCIJBSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 457.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.0 7.72 9.9 ChEMBL
κ OPRK Guinea pig Opioid A pKd 8.8 8.8 8.8 ChEMBL
μ OPRM Human Opioid A pKi 9.8 9.88 9.9 ChEMBL
δ OPRD Human Opioid A pKi 7.0 7.45 8.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database