tripelennamine


SMILES CN(CCN(c1ccccn1)Cc1ccccc1)C
InChIKey UFLGIAIHIAPJJC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 255.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKd 8.0 8.0 8.0 Guide to Pharmacology
H1 HRH1 Rat Histamine A pKi 7.46 7.46 7.46 PDSP Ki database
H1 HRH1 Human Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pIC50 7.4 7.4 7.4 Guide to Pharmacology
H1 HRH1 Human Histamine A pIC50 7.4 7.4 7.4 ChEMBL
H1 HRH1 Human Histamine A pIC50 8.13 8.13 8.13 Drug Central