Chembl317233

Chemical Properties

SMILES Cc1cc(C)nc(OC(C(=O)O)C(OCCc2ccccc2)(c2ccccc2)c2ccccc2)n1
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight 468.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey QWDHLTWAAVZDIR-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETB EDNRB Human Endothelin A pKi 6.64 6.64 6.64 ChEMBL
ETA EDNRA Human Endothelin A pKi 7.6 7.6 7.6 ChEMBL