vasopressin


SMILES None
InChIKey KBZOIRJILGZLEJ-LGYYRGKSSA-N
Sequence CYFQNCPRG

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7BB7 7KH0 7BB6 7DW9 7R0C

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 8.5 8.9 9.3 Guide to Pharmacology
V1A V1AR Rat Vasopressin and oxytocin A pKi 8.4 8.4 8.4 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 7.9 8.5 9.1 Guide to Pharmacology
V1B V1BR Rat Vasopressin and oxytocin A pKi 9.9 9.9 9.9 Guide to Pharmacology
V2 V2R Bovine Vasopressin and oxytocin A pKd 8.82 8.82 8.82 ChEMBL
V1B V1BR Rat Vasopressin and oxytocin A pKi 9.54 9.54 9.54 ChEMBL
V1A V1AR Rat Vasopressin and oxytocin A pKd 9.19 9.19 9.19 ChEMBL
V1A V1AR Rat Vasopressin and oxytocin A pKi 8.81 8.81 8.81 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pKd 8.82 8.82 8.82 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pKi 9.35 9.35 9.35 ChEMBL
OT OXYR Rat Vasopressin and oxytocin A pKi 8.93 8.93 8.93 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pKi 8.7 9.06 9.31 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 7.92 8.48 8.78 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 7.5 8.53 8.92 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 8.4 9.0 9.59 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pKi 9.0 9.25 9.5 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKi 7.3 8.3 9.3 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V2 V2R Pig Vasopressin and oxytocin A pIC50 8.48 8.48 8.48 ChEMBL
V1A V1AR Rat Vasopressin and oxytocin A pEC50 10.15 10.18 10.2 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pEC50 7.96 8.35 8.7 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pEC50 7.39 8.13 10.0 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pEC50 10.28 10.29 10.3 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pIC50 6.62 6.62 6.62 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pEC50 7.5 9.09 9.63 ChEMBL