CHEMBL321492


SMILES COc1c(C(=O)N[C@H]2CN(Cc3ccccc3)C[C@H]2C)cc(Br)c2ccccc12
InChIKey ZLQMLDGHTKCIRQ-ZHRRBRCNSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 452.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.33 5.37 5.4 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.57 8.07 8.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.41 6.65 6.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.54 6.72 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database