CHEMBL302075


SMILES Clc1ccc(N2CCN(C[C@H]3C[C@@H]3c3ccccc3)CC2)c(Cl)c1
InChIKey AOSAPZYJOHCROI-SJLPKXTDSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 360.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.62 7.96 8.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.74 6.88 7.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 8.05 8.14 8.22 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.03 7.11 7.19 ChEMBL