YM348


SMILES CCc1oc2c(c1)c1c(cc2)cnn1C[C@@H](N)C
InChIKey QLOOWOVVZLBYHU-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 243.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.6 8.6 8.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.05 9.05 9.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 8.49 8.49 8.49 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 9.0 9.0 9.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.03 7.03 7.03 ChEMBL