zaprinast
| SMILES | CCCOc1ccccc1c1nc(=O)c2c(n1)[nH][nH]n2 |
| InChIKey | REZGGXNDEMKIQB-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 4 |
| Molecular weight (Da) | 271.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GPR35 | GPR35 | Human | A orphans | A | pKi | 6.21 | 6.3 | 6.4 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GPR35 | GPR35 | Human | A orphans | A | pEC50 | 6.1 | 6.1 | 6.1 | Guide to Pharmacology |
| GPR35 | Q33BM1 | Rat | A orphans | A | pEC50 | 7.8 | 7.8 | 7.8 | Guide to Pharmacology |
| GPR35 | GPR35 | Mouse | A orphans | A | pEC50 | 6.01 | 6.01 | 6.01 | ChEMBL |
| GPR35 | Q33BM1 | Rat | A orphans | A | pEC50 | 7.21 | 7.21 | 7.21 | ChEMBL |
| GPR35 | GPR35 | Human | A orphans | A | pEC50 | 5.21 | 6.27 | 9.15 | ChEMBL |
| GPR35 | GPR35 | Human | A orphans | A | pIC50 | 4.98 | 6.03 | 7.32 | ChEMBL |