LYSOPHOSPHATIDIC ACID


SMILES CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O
InChIKey WRGQSWVCFNIUNZ-GDCKJWNLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 20
Molecular weight (Da) 436.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Structure pdb 8WRB 8IZB

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
LPA1 LPAR1 Human Lysophospholipid (LPA) A pKd 8.25 8.25 8.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
LPA4 LPAR4 Mouse Lysophospholipid (LPA) A pEC50 6.58 6.58 6.58 ChEMBL
LPA6 LPAR6 Human Lysophospholipid (LPA) A pEC50 6.01 6.01 6.01 ChEMBL
LPA4 LPAR4 Human Lysophospholipid (LPA) A pEC50 8.09 8.09 8.09 ChEMBL
LPA5 LPAR5 Human Lysophospholipid (LPA) A pEC50 6.29 7.18 7.92 ChEMBL
LPA2 LPAR2 Human Lysophospholipid (LPA) A pEC50 7.54 7.99 8.7 ChEMBL
LPA3 LPAR3 Human Lysophospholipid (LPA) A pEC50 6.08 6.76 7.11 ChEMBL
LPA1 LPAR1 Human Lysophospholipid (LPA) A pEC50 6.08 7.22 7.77 ChEMBL