Chembl1178932

Chemical Properties

SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight 414.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey PEJFBWCDCTVGLS-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 5.0 5.19 5.52 ChEMBL
α2A ADA2A Bovine Adrenoceptors A pIC50 5.3 5.3 5.3 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pIC50 5.1 5.26 5.52 ChEMBL
D1 DRD1 Bovine Dopamine A pIC50 4.3 4.41 4.52 ChEMBL
D2 DRD2 Bovine Dopamine A pIC50 7.0 7.57 8.0 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 4.52 4.74 5.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 8.1 8.6 9.0 ChEMBL